The neuromechanics of animal locomotion: From biology to robotics and back

P Ramdya, AJ Ijspeert - Science Robotics, 2023 - science.org
Robotics and neuroscience are sister disciplines that both aim to understand how agile,
efficient, and robust locomotion can be achieved in autonomous agents. Robotics has …

Volume electron microscopy

CJ Peddie, C Genoud, A Kreshuk, K Meechan… - Nature Reviews …, 2022 - nature.com
Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

Oligodendrocyte precursor cells ingest axons in the mouse neocortex

JA Buchanan, L Elabbady, F Collman… - Proceedings of the …, 2022 - National Acad Sciences
Neurons in the developing brain undergo extensive structural refinement as nascent circuits
adopt their mature form. This physical transformation of neurons is facilitated by the …

[HTML][HTML] Ascending neurons convey behavioral state to integrative sensory and action selection brain regions

CL Chen, F Aymanns, R Minegishi, VDV Matsuda… - Nature …, 2023 - nature.com
Knowing one's own behavioral state has long been theorized as critical for contextualizing
dynamic sensory cues and identifying appropriate future behaviors. Ascending neurons …

[HTML][HTML] Volume EM: a quiet revolution takes shape

LM Collinson, C Bosch, A Bullen, JJ Burden… - Nature …, 2023 - nature.com
Volume electron microscopy (vEM) is a group of techniques that reveal the 3D ultrastructure
of cells and tissues through continuous depths of at least 1 micrometer. A burgeoning …

Functional connectomics spanning multiple areas of mouse visual cortex

MICrONS Consortium, JA Bae, M Baptiste, CA Bishop… - BioRxiv, 2021 - biorxiv.org
To understand the brain we must relate neurons' functional responses to the circuit
architecture that shapes them. Here, we present a large functional connectomics dataset …

[HTML][HTML] Neuronal wiring diagram of an adult brain

S Dorkenwald, A Matsliah, AR Sterling, P Schlegel… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Connections between neurons can be mapped by acquiring and analyzing electron
microscopic (EM) brain images. In recent years, this approach has been applied to chunks of …

Interactions of glial cells with neuronal synapses, from astrocytes to microglia and oligodendrocyte lineage cells

Y Liu, X Shen, Y Zhang, X Zheng, C Cepeda, Y Wang… - Glia, 2023 - Wiley Online Library
The mammalian brain is a complex organ comprising neurons, glia, and more than 1× 1014
synapses. Neurons are a heterogeneous group of electrically active cells, which form the …

[PDF][PDF] Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch

A Handler, Q Zhang, S Pang, TM Nguyen, M Iskols… - Neuron, 2023 - cell.com
Across mammalian skin, structurally complex and diverse mechanosensory end organs
respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces …

Structured cerebellar connectivity supports resilient pattern separation

TM Nguyen, LA Thomas, JL Rhoades, I Ricchi… - Nature, 2023 - nature.com
The cerebellum is thought to help detect and correct errors between intended and executed
commands, and is critical for social behaviours, cognition and emotion,,–. Computations for …