Accurate segmentation of the thyroid gland in ultrasound images is an essential initial step
in distinguishing between benign and malignant nodules, thus facilitating early diagnosis …

Synthetic lethality (SL), a genetic concept, has revolutionized the development of antitumor
therapies by providing avenues to target previously “undruggable” targets with enhanced …

Cancer is a multifaceted disease that results from co-mutations of multi biological molecules.
A promising strategy for cancer therapy involves in exploiting the phenomenon of Synthetic …

Abstract In recent years, Graph Neural Networks (GNNs) have garnered significant attention,
with a notable focus on Graph Structure Learning (GSL), a branch dedicated to optimizing …

Computational drug repositioning which accelerates the process of drug development is
able to reduce the cost in terms of time and money dramatically which brings promising and …

Computational synthetic lethality (SL) method has become a promising strategy to identify
SL gene pairs for targeted cancer therapy and cancer medicine development. Feature …

Computational methods to discover potential synthetic lethality (SL) pairs has become a
promising strategy for targeted cancer therapy and cancer medicine development. Despite …

Introduction The signal transducer and activator of transcription-1 (STAT-1) are tightly
controlled signaling pathways, with induced genes acting as positive and negative …