The eye and the brain are immunologically privileged sites, a property previously attributed
to the lack of a lymphatic circulation. However, recent tracking studies confirm that these …

Uveitis is a sight-threatening disease caused by autoimmune or infection-related immune
responses. Studies in experimental autoimmune uveitis and in human diseases imply that …

Mesenchymal stem/progenitor cells (MSCs) were reported to enhance the survival of cellular
and organ transplants. However, their mode of action was not established. We here used a …

The eye and the brain are prototypical tissues manifesting immune privilege (IP) in which
immune responses to foreign antigens, particularly alloantigens are suppressed, and even …

Purpose.: The aim of this study was to determine and characterize the effect of topical
application of benzalkonium chloride (BAK) on corneal nerves in vivo and in vitro. Methods …

Purpose: To report the incidence of early allograft rejection after Descemet membrane
endothelial keratoplasty (DMEK), that is, transplantation of isolated Descemet membrane …

Immune privilege (IP), a term introduced to explain the unpredicted acceptance of allogeneic
grafts by the eye and the brain, is considered a unique property of these tissues. However …

Experimental autoimmune uveoretinitis (EAU) serves as an animal model for human uveitis.
EAU is inducible in animals by peripheral immunization with proteins found in the retina that …

Uveitis is underappreciated as a sight-threatening cause of blindness. There are two broad
causative classes of uveitis: infectious and non-infectious. Non-infectious uveitis is …

Purpose.: In addition to Langerhans cells (LCs), other dendritic cells (CD11c+) have recently
been shown to express Langerin (c-type lectin). In skin,(non-LC) Langerin+ dendritic cells …