Protein glycosylation, including sialylation, involves complex and frequent post-translational
modifications, which play a critical role in different biological processes. The conjugation of …

GDP-fucose is synthesised via two pathways: de novo and salvage. The first uses GDP-
mannose as a substrate, and the second uses free fucose. To date, these pathways have …

Sialyltransferases responsible for glycoprotein sialylation are key regulators in cancer
progression. Although ST3 β‑galactoside α‑2, 3‑sialyltransferase 4 (ST3GAL4), an important …

Sialyltransferases are enzymes that play a crucial role in regulating cancer progression by
modifying glycoproteins through sialylation. In particular, the ST3 beta-galactoside alpha-2 …

Protein-protein interactions (PPIs) play fundamental roles in many biological processes
including the functioning of glycosylation machineries present in the endoplasmic reticulum …

Die Glykosylierung ist eine wichtige co-und posttranslationale Modifikation von Proteinen,
die für deren korrekte Faltung, Funktionalität und Interaktionen benötigt wird. Wird dieser …