Microbial translocation in the pathogenesis of HIV infection and AIDS

G Marchetti, C Tincati, G Silvestri - Clinical microbiology reviews, 2013 - Am Soc Microbiol
In pathogenic simian immunodeficiency virus (SIV) and human immunodeficiency virus
(HIV) infections, the translocation of microbial products from the gastrointestinal (GI) tract to …

Alcohol use and human immunodeficiency virus (HIV) infection: current knowledge, implications, and future directions

EC Williams, JA Hahn, R Saitz, K Bryant… - Alcoholism: Clinical …, 2016 - Wiley Online Library
Alcohol use is common among people living with human immunodeficiency virus (HIV). In
this narrative review, we describe literature regarding alcohol's impact on transmission, care …

Cross-sectional Comparison of the Prevalence of Age-Associated Comorbidities and Their Risk Factors Between HIV-Infected and Uninfected Individuals: The AGEh …

J Schouten, FW Wit, IG Stolte… - Clinical Infectious …, 2014 - academic.oup.com
Age-associated comorbidities (cardiovascular and renal disease) were more prevalent
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …

Cardiovascular disease and thrombosis in HIV infection

MV Perkins, SB Joseph, DP Dittmer… - … , and vascular biology, 2023 - Am Heart Assoc
HIV infection has transitioned from an acute, fatal disease to a chronic one managed by
antiretroviral therapy. Thus, the aging population of people living with HIV (PLWH) continues …

Microbial translocation in HIV infection: causes, consequences and treatment opportunities

NG Sandler, DC Douek - Nature Reviews Microbiology, 2012 - nature.com
Systemic immune activation is increased in HIV-infected individuals, even in the setting of
virus suppression with antiretroviral therapy. Although numerous factors may contribute …

Environmental enteropathy: critical implications of a poorly understood condition

PS Korpe, WA Petri - Trends in molecular medicine, 2012 - cell.com
Environmental enteropathy (also called tropical enteropathy) is a subclinical condition
caused by constant fecal–oral contamination and resulting in blunting of intestinal villi and …

Microbial translocation and microbiome dysbiosis in HIV-associated immune activation

AS Zevin, L McKinnon, A Burgener… - Current Opinion in HIV …, 2016 - journals.lww.com
Microbial translocation and microbiome dysbiosis in HIV-asso... : Current Opinion in HIV and
AIDS Microbial translocation and microbiome dysbiosis in HIV-associated immune activation …

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

NJ Dharan, P Yeh, M Bloch, MM Yeung, D Baker… - Nature medicine, 2021 - nature.com
People with human immunodeficiency virus (HIV) have higher rates of certain comorbidities,
particularly cardiovascular disease and cancer, than people without HIV,,,–. In view of …

Microbial translocation, immune activation, and HIV disease

NR Klatt, NT Funderburg, JM Brenchley - Trends in microbiology, 2013 - cell.com
The advent of combination antiretroviral therapy (cART) has significantly improved the
prognosis of human immunodeficiency virus (HIV)-infected individuals. However, individuals …

Microbial translocation across the GI tract

JM Brenchley, DC Douek - Annual review of immunology, 2012 - annualreviews.org
The lumen of the gastrointestinal (GI) tract is home to an enormous quantity of different
bacterial species, our microbiota, that thrive in an often symbiotic relationship with the host …