Animal speciation often involves novel behavioral features that rely on nervous system
evolution. Human-specific brain features have been proposed to underlie specialized …

Disease gene discovery on chromosome (chr) X is challenging owing to its unique modes of
inheritance. We undertook a systematic analysis of human chrX genes. We observe a higher …

Autism spectrum disorder (ASD) displays a notable male bias in prevalence. Research into
rare (< 0.1) genetic variants on the X chromosome has implicated over 20 genes in ASD …

The enhanced cognitive abilities characterizing the human species result from specialized
features of neurons and circuits. Here, we report that the hominid-specific gene LRRC37B …

X-linked epilepsies are a heterogeneous group of epileptic conditions, which often overlap
with X-linked intellectual disability. To date, various X-linked genes responsible for epilepsy …

Summary Objective Fibroblast Growth Factor 12 (FGF12) may represent an important
modulator of neuronal network activity and has been associated with developmental and …

Epidemiological studies regarding the relationship between per-and polyfluoroalkyl
substances (PFAS) and DNA methylation were limited. We investigated the associations of …

Developmental and epileptic encephalopathies (DEEs), a class of devastating neurological
disorders characterized by recurrent seizures and exacerbated by disruptions to …

Galectins constitute a class of lectins that specifically interact with β-galactoside sugars in
glycoconjugates and are implicated in diverse cellular processes, including transport …

Developmental and epileptic encephalopathies (DEE) are a genetically heterogeneous
group of disorders characterised by early onset epilepsy, epileptiform activity on …