Complications of intravitreal injections: 2022

D Patel, SN Patel, V Chaudhary… - Current Opinion in …, 2022 - journals.lww.com
Intravitreal injections continue to be one of the most commonly performed procedures by
ophthalmologists. Although the injections are generally well tolerated, sight-threatening …

Signaling pathways driving ocular malignancies and their targeting by bioactive phytochemicals

CR Croley, J Pumarol, BE Delgadillo, AC Cook… - Pharmacology & …, 2023 - Elsevier
Ocular cancers represent a rare pathology. The American Cancer Society estimates that
3,360 cases of ocular cancer occur annually in the United States. The major types of cancers …

Modulatory effect of amifostine (WR-1065) against genotoxicity and oxidative stress induced by methotrexate in human umbilical vein endothelial cells (HUVECs)

S Aghajanshakeri, A Salmanmahiny… - Toxicology …, 2023 - Taylor & Francis
Amifostine is used in chemotherapy and radiotherapy as a cytoprotective adjuvant alongside
DNA-binding chemotherapeutic agents. It functions by reducing free radicals and detoxifying …

Efficacy and safety of intravitreal methotrexate for vitreo‐retinal lymphoma–20 years of experience

Z Habot‐Wilner, S Frenkel… - British Journal of …, 2021 - Wiley Online Library
Vitreo‐retinal lymphoma (VRL) is the most common intraocular lymphoma and is highly
associated with central nervous system (CNS) lymphoma (CNSL), both posing a therapeutic …

[HTML][HTML] Inhibition of proliferative vitreoretinopathy by a newly developed methotrexate loaded drug carrier in vitro

SS Arrow, SC Felis, A Hillenmayer, LD Strehle… - Biomedicine & …, 2023 - Elsevier
Purpose Repeated intravitreal injections of methotrexate for proliferative vitreoretinopathy, a
rare ocular condition that can cause vision loss, have shown beneficial effects in recent …

A comprehensive review of intravitreal immunosuppressants and biologicals used in ophthalmology

N Hasan, R Chawla, N Shaikh… - Therapeutic …, 2022 - journals.sagepub.com
Systemic immunosuppressants and biologicals have been a valuable tool in the treatment of
inflammatory diseases and malignancies. The safety profile of these drugs has been …

Corneal toxicity of intravitreal methotrexate used for the treatment of proliferative vitreoretinopathy in silicone oil-filled eyes: a case series

JH Shen-Sampas, TR Ahmad, JM Stewart - Cornea, 2022 - journals.lww.com
Purpose: The purpose of this study was to evaluate the corneal toxicity of intravitreal
methotrexate used for the prevention of proliferative vitreoretinopathy (PVR). Methods: In this …

Ocular surface complications of local anticancer drugs for treatment of ocular tumors

J Moon, SH Choi, MJ Lee, DH Jo, UC Park, SO Yoon… - The Ocular Surface, 2021 - Elsevier
Local chemotherapy is increasingly used, either in combination with surgery or as
monotherapy, for management of ocular tumors. Yet many of the local chemotherapeutic …

[HTML][HTML] Clinical utility of cytokine analysis in the diagnosis and efficacy monitoring of vitreoretinal lymphoma

H Kang, Y Tao - International Journal of Ophthalmology, 2022 - ncbi.nlm.nih.gov
AIM To investigate the value of cytokine analysis in aqueous humor (AH) for discriminating
vitreoretinal lymphoma (VRL) from uveitis and for evaluating the efficacy of intravitreal …

[HTML][HTML] Primary Intraocular Lymphoma

S Simakurthy, S Jena, K Tripathy - 2022 - europepmc.org
Objectives: Describe the etiology of primary intraocular lymphoma. Summarize the relevant
history and clinical findings of patients with primary intraocular lymphoma. Review the …