Metastasis, the dissemination of cancer cells from primary tumors, represents a major hurdle
in the treatment of cancer. The epithelial-mesenchymal transition (EMT) has been studied in …

Cadherins are homophilic adhesion molecules with important functions in cell-cell adhesion,
tissue morphogenesis, and cancer. In epithelial cells, E-cadherin accumulates at areas of …

In the context of cancer, E-cadherin has traditionally been categorized as a tumor
suppressor, given its essential role in the formation of proper intercellular junctions, and its …

We focus on unique roles of miR‐200c in breast, ovarian, and endometrial cancers.
Members of the miR‐200 family target ZEB1, a transcription factor which represses E …

Epithelial-cadherin (E-cadherin; encoded by CDH1) is a member of the classical cadherins
(the others being neural cadherin (N-cadherin) and vascular endothelial cadherin (VE …

Epithelial–mesenchymal transition (EMT) plays a crucial role in hepatocellular carcinoma
(HCC) progression. Hypoxia and excessive transforming growth factor-β (TGF-β) have been …

Cancer progression and metastasis are processes that involve significant cellular changes.
Many of these changes include alterations in the activity of the Rho GTPase family of …

Tumor growth and metastatic dissemination rely on cellular plasticity. Among the different
phenotypes acquired by cancer cells, epithelial to mesenchymal transition (EMT) has been …

Tumor cell migration is a well-orchestrated multistep process that drives cancer
development and metastasis. Previous data indicated that CD146 expression correlates with …

Abstract The (iso-) flavonoids chrysin 1, apigenin 2, genistein 3 and their homoleptic copper
(II) complexes 4–6 were compared for general cancer cell growth inhibition and for …