Horizontal gene transfer and adaptive evolution in bacteria

BJ Arnold, IT Huang, WP Hanage - Nature Reviews Microbiology, 2022 - nature.com
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …

Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Microbiome definition re-visited: old concepts and new challenges

G Berg, D Rybakova, D Fischer, T Cernava… - Microbiome, 2020 - Springer
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in …

Rapid evolutionary turnover of mobile genetic elements drives bacterial resistance to phages

FA Hussain, J Dubert, J Elsherbini, M Murphy… - Science, 2021 - science.org
Although it is generally accepted that phages drive bacterial evolution, how these dynamics
play out in the wild remains poorly understood. We found that susceptibility to viral killing in …

Diversity within species: interpreting strains in microbiomes

T Van Rossum, P Ferretti, OM Maistrenko… - Nature Reviews …, 2020 - nature.com
Studying within-species variation has traditionally been limited to culturable bacterial
isolates and low-resolution microbial community fingerprinting. Metagenomic sequencing …

The plant microbiome: from ecology to reductionism and beyond

CR Fitzpatrick, I Salas-González… - Annual review of …, 2020 - annualreviews.org
Methodological advances over the past two decades have propelled plant microbiome
research, allowing the field to comprehensively test ideas proposed over a century ago and …

Good microbes, bad genes? The dissemination of antimicrobial resistance in the human microbiome

A Crits-Christoph, HA Hallowell, K Koutouvalis… - Gut …, 2022 - Taylor & Francis
ABSTRACT A global rise in antimicrobial resistance among pathogenic bacteria has proved
to be a major public health threat, with the rate of multidrug-resistant bacterial infections …

Environmental fluctuations and their effects on microbial communities, populations and individuals

J Nguyen, J Lara-Gutiérrez… - FEMS microbiology …, 2021 - academic.oup.com
From the homeostasis of human health to the cycling of Earth's elements, microbial activities
underlie environmental, medical and industrial processes. These activities occur in chemical …

Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes

V Aggarwala, I Mogno, Z Li, C Yang, GJ Britton… - Nature …, 2021 - nature.com
Fecal microbiota transplantation (FMT) has been successfully applied to treat recurrent
Clostridium difficile infection in humans, but a precise method to measure which bacterial …

Resolving the structure of phage–bacteria interactions in the context of natural diversity

KM Kauffman, WK Chang, JM Brown… - Nature …, 2022 - nature.com
Microbial communities are shaped by viral predators. Yet, resolving which viruses (phages)
and bacteria are interacting is a major challenge in the context of natural levels of microbial …