Affinity proteomics is the field of proteome analysis based on the use of antibodies and other
binding reagents as protein-specific detection probes. In this review, the particular strengths …

Behcet′ s disease is a multisystem disease characterized by recurrent oral and genital
ulcers, relapsing uveitis, mucocutaneous, articular, gastrointestinal, neurologic, and vascular …

The adaptive immune system is thought to be a rich source of protein biomarkers, but
diagnostically useful antibodies remain unknown for a large number of diseases. This is, in …

Profiling the autoantibody repertoire with large antigen collections is emerging as a powerful
tool for the identification of biomarkers for autoimmune diseases. Here, a systematic and …

Objective Biological therapies, which include antitumour necrosis factor-α and T-cell
inhibitors, are potentially effective treatments for psoriatic arthritis (PsA) but are costly and …

Purpose. ITP is the most prevalent autoimmune blood disorder. The lack of predictive
biomarkers for therapeutic response is a major challenge for physicians caring of chronic …

Purpose.: To investigate the presence of biomarkers in aqueous humor (AH) from patients
with uveitis associated with juvenile idiopathic arthritis (JIA). Methods.: AH (n= 73) and …

Th17 cells play a critical role in the pathogenesis of autoimmune diseases, including
multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome …

Current approaches within affinity-based proteomics are driven both by the accessibility and
availability of antigens and capture reagents, and by suitable multiplexed technologies onto …

ABSTRACT Introduction: The heterogeneity of Rheumatoid Arthritis (RA) and the absence of
clinical tests accurate enough to identify the early stages of this disease have hampered its …