SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Sporadic cerebral small vessel disease (SVD) is a major contributor to vascular cognitive
impairment and dementia in the aging human brain. On neuropathology, sporadic SVD is …

A leading cause of white matter (WM) injury in older individuals is cerebral small vessel
disease (SVD). Cerebral SVD is the most prevalent vascular contributor to cognitive …

BACKGROUND AND PURPOSE: Whole-brain network connectivity has been shown to be a
useful biomarker of cerebral amyloid angiopathy and related cognitive impairment. We …

While cerebrovascular disease can be observed in vivo using MRI, the multiplicity and
heterogeneity in the mechanisms of cerebrovascular damage impede accounting for these …

Neuroimaging features of small vessel disease (SVD) are highly prevalent in older
adulthood and associated with significant variability in clinical symptoms, yet the factors …

Aging is accompanied by structural brain changes that are thought to underlie cognitive
decline and dementia. Yet little is known regarding the association between increasing age …

INTRODUCTION We investigated whether retinal capillary perfusion is a biomarker of
cerebral small vessel disease and impaired cognition among Black Americans, an …

Background Peak width of skeletonized mean diffusivity (PSMD) is a promising diffusion
tensor imaging (DTI) marker that shows consistent and strong cognitive associations in the …

Background: Cerebral small vessel disease (SVD) and Alzheimer's disease pathology,
namely amyloid-(A) deposition, commonly co-occur. Exactly how they interact remains …