[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …
is a main driving force in many severe human diseases including cancer. As such, tumor …
Designing a broad-spectrum integrative approach for cancer prevention and treatment
Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …
notable successes in some cancers; however, significant problems remain with this …
Green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG): a time for a new player in the treatment of respiratory diseases?
D Mokra, J Adamcakova, J Mokry - Antioxidants, 2022 - mdpi.com
(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …
Plants and their active compounds: natural molecules to target angiogenesis
K Lu, M Bhat, S Basu - Angiogenesis, 2016 - Springer
Angiogenesis, or new blood vessel formation, is an important process in the pathogenesis of
several diseases and thus has been targeted for the prevention and treatment for many …
several diseases and thus has been targeted for the prevention and treatment for many …
[HTML][HTML] ω-3 polyunsaturated fatty acids inhibit the proliferation of the lung adenocarcinoma cell line A549 in vitro
QH Yao, XC Zhang, T Fu, JZ Gu… - Molecular …, 2014 - spandidos-publications.com
Abstract ω-3 polyunsaturated fatty acids (n-3 PUFA), in particular the marine-derived forms
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been demonstrated to …
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been demonstrated to …
[HTML][HTML] A broad-spectrum integrative design for cancer prevention and therapy
Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …
notable successes in some cancers; however, significant problems remain with this …
Polyphenol-based nutraceuticals for the control of angiogenesis: Analysis of the critical issues for human use
L Morbidelli - Pharmacological Research, 2016 - Elsevier
Angiogenesis, the formation of new blood-vessel, is crucial in the pathogenesis of several
diseases, and thus represents a druggable target for the prevention and treatment of …
diseases, and thus represents a druggable target for the prevention and treatment of …
Antiangiogenic compounds: well-established drugs versus emerging natural molecules
A Ribeiro, RMV Abreu, MM Dias, MF Barreiro… - Cancer Letters, 2018 - Elsevier
Angiogenesis is the natural and physiologic process of growing blood vessels from pre-
existing ones. Pathological angiogenesis occurs when the precise balance of all the …
existing ones. Pathological angiogenesis occurs when the precise balance of all the …
Pharmacokinetic evaluation of callistemon viminalis derived natural compounds as targeted inhibitors against δ-opioid receptor and farnesyl transferase
Introduction: Chronic inflammation of organs has been linked with various steps involved in
carcinogenesis. Delta-opioid receptors (DOR) and farnesyl transferase (FT) inhibitors have …
carcinogenesis. Delta-opioid receptors (DOR) and farnesyl transferase (FT) inhibitors have …
Computational assessment of pigment epithelium-derived factor as an anti-cancer protein during its interaction with the receptors
B Shahbazi, SS Arab, L Mafakher… - Journal of …, 2023 - Taylor & Francis
Pigment epithelium-derived factor (PEDF) is a member of the serine proteinase inhibitor
(serpin) with antiangiogenic, anti-tumorigenic, antioxidant, anti-atherosclerosis …
(serpin) with antiangiogenic, anti-tumorigenic, antioxidant, anti-atherosclerosis …