Multiple sclerosis and circadian rhythms: Can diet act as a treatment?

O Pivovarova‐Ramich, HG Zimmermann… - Acta …, 2023 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune inflammatory and neurodegenerative disease of
the central nervous system (CNS) with increasing incidence and prevalence. MS is …

Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation

UK Zettl, PS Rommer, O Aktas, T Wagner… - Expert review of …, 2023 - Taylor & Francis
Introduction Interferon beta (IFN beta) preparations are an established group of drugs used
for immunomodulation in patients with multiple sclerosis (MS). Subcutaneously (sc) applied …

Association between anti-CD20 therapies and COVID-19 severity among patients with relapsing-remitting and progressive multiple sclerosis

E Januel, D Hajage, P Labauge, E Maillart… - JAMA Network …, 2023 - jamanetwork.com
Importance In patients with multiple sclerosis (MS), factors associated with severe COVID-19
include anti-CD20 therapies and neurologic disability, but it is still unclear whether these 2 …

Neuroinflammatory disorders of the brain and inner ear: a systematic review of auditory function in patients with migraine, multiple sclerosis, and neurodegeneration to …

A Di Stadio, P De Luca, N Koohi, D Kaski… - Frontiers in …, 2023 - frontiersin.org
Background Hearing can be impaired in many neurological conditions and can even
represent a forme fruste of specific disorders. Auditory function can be measured by either …

The impact of menopause on multiple sclerosis

F Bridge, H Butzkueven, A Van der Walt… - Autoimmunity …, 2023 - Elsevier
Menopause, defined as the permanent cessation of ovarian function, represents a period of
significant fluctuation in sex hormone concentrations. Sex hormones including oestrogen …

Adverse Events Associated With Disease-Modifying Drugs for Multiple Sclerosis: A Multiregional Population-Based Study

HS Ng, F Zhu, Y Zhao, S Yao, X Lu, O Ekuma… - Neurology, 2024 - AAN Enterprises
Background and Objectives It is not possible to fully establish the safety of a disease-
modifying drug (DMD) for multiple sclerosis (MS) from randomized controlled trials as only …

Multiple sclerosis disease-modifying drug use by immigrants: a real-world study

J Graf, HS Ng, F Zhu, Y Zhao, JMA Wijnands… - Scientific Reports, 2023 - nature.com
Little is known about disease-modifying drug (DMD) initiation by immigrants with multiple
sclerosis (MS) in countries with universal health coverage. We assessed the association …

Disease-modifying drugs, multiple sclerosis and infection-related healthcare use in British Columbia, Canada: a population-based study

J Graf, HS Ng, F Zhu, Y Zhao, JMA Wijnands… - The Lancet Regional …, 2024 - thelancet.com
Background Much remains unknown surrounding the disease-modifying drugs (DMDs) used
to treat multiple sclerosis and infection-related healthcare use in the 'real-world'setting. We …

Narrative Review on the Use of Cladribine Tablets as Exit Therapy for Stable Elderly Patients with Multiple Sclerosis

J de Seze, D Dive, X Ayrignac, G Castelnovo… - Neurology and …, 2024 - Springer
The number of ageing people with relapsing multiple sclerosis (RMS) is increasing. The
efficacy of disease-modifying therapies (DMTs) for RMS declines with age. Also, older …

Switching to second line MS disease-modifying therapies is associated with decreased relapse rate

JJ Marriott, O Ekuma, R Fransoo, RA Marrie - Frontiers in Neurology, 2023 - frontiersin.org
Background and objectives While randomized, controlled trials (RCTs) are the gold standard
for determining treatment efficacy, they do not capture the effectiveness of treatment during …