This review focuses on cytotoxic rhenium compounds in terms of IC 50 values, their mode of
action in biological systems and their status in clinical trials. Biological studies of different …

Medical device biocompatibility testing is used to evaluate the risk of adverse effects on
tissues from exposure to leachates/extracts. A battery of tests is typically recommended in …

Abstract Inosine-5′-monophosphate dehydrogenase (IMPDH), a key regulatory enzyme in
purine nucleotide biosynthesis, dynamically assembles filaments in response to changes in …

Abstract The 2, 2′-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay is a valid
and commonly test used to measure the total antioxidant capacity in natural extracts. The …

In the quest for new antimicrobial materials, hydrogels of Fmoc-protected peptides and
amino acids have gained momentum due to their ease of synthesis and cost effectiveness; …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that has been
associated with the deposition of aggregates of superoxide dismutase 1 (SOD1). Effective …

Saccharomyces yeasts are able to ferment simple sugars to generate levels of ethanol that
are toxic to other yeasts and bacteria. The tolerance to ethanol of different yeasts depends …

Background Enhanced metabolic plasticity and diversification of energy production is a
hallmark of highly proliferative breast cancers. This contributes to poor pharmacotherapy …

Failure to recognize important features of a drug's pharmacokinetic characteristics is a key
cause of inappropriate dose and schedule selection, and can lead to reduced efficacy and …

Inosine 5′ monophosphate dehydrogenase (IMPDH) is a critical regulatory enzyme in
purine nucleotide biosynthesis that is inhibited by the downstream product GTP. Multiple …