Efficient biotransformation of naringenin to naringenin α-glucoside, a novel α-glucosidase inhibitor, by amylosucrase from Deinococcus wulumuquiensis

SJ Yu, YS So, C Lim, CH Cho, SG Lee, SH Yoo… - Food Chemistry, 2024 - Elsevier
Amylosucrase (ASase) efficiently biosynthesizes α-glucoside using flavonoids as acceptor
molecules and sucrose as a donor molecule. Here, ASase from Deinococcus …

Biotransformation of hydroquinone into α-arbutin by transglucosylation activity of a metagenomic amylosucrase

N Agarwal, AK Rai, SP Singh - 3 Biotech, 2021 - Springer
Arbutin is a naturally occurring glycosylated product of hydroquinone. With the ability to
interrupt melanin biosynthesis in epidermal cells, it is a promising cosmetic ingredient. In this …

Efficient and novel biosynthesis of myricetin α-triglucoside with improved solubility using amylosucrase from Deinococcus deserti

JK Im, DH Seo, JS Yu, SH Yoo - International Journal of Biological …, 2024 - Elsevier
Abstract Although myricetin (3, 3′, 4′, 5, 5′, 7-hexahydroxyflavone, MYR) has a high
antioxidant capacity and health functions, its use as a functional food material is limited …

Characterization of a unique pH-dependent amylosucrase from Deinococcus cellulosilyticus

CY Lee, YS So, MC Lim, S Jeong, SH Yoo… - International Journal of …, 2024 - Elsevier
Abstract The amylosucrase (ASase, EC 2.4. 1.4) utilizes sucrose as the sole substrate to
catalyze multifunctional reactions. It can naturally synthesize α-1, 4-linked glucans such as …

Improving the transglycosylation reaction of amylosucrase from Deinococcus geothermalis variant for increased flavonoid reactivity

SJ Ryu, YS So, TG Nam, WJ Lee, SH Yoo, DH Seo - Food Bioscience, 2024 - Elsevier
Abstract Amylosucrase (ASase) from Deinococcus geothermalis (DgAS) is involved in the
highest number of glycotransfer reactions with different flavonoids as acceptor molecules …

Comparative study on four amylosucrases from Bifidobacterium species

SY Kim, DH Seo, SH Kim, YS Hong, JH Lee… - International journal of …, 2020 - Elsevier
Amylosucrase (ASase) is α-glucan-producing enzyme. Four putative ASase genes (bdas,
blas, bpas, and btas) were cloned from Bifidobacterium sp. and expressed in Escherichia …

Production of resveratrol glucosides and its cosmetic activities

SB Thapa, J Jeon, BG Park, D Shim, CS Lee, JK Sohng - Cosmetics, 2023 - mdpi.com
A biocatalytic system that could produce bioactive resveratrol poly-glucosides, using
sucrose as a low-cost source of UDP-glucose donors and amylosucrase DgAS from …

Molecular Structure of Flavonoids Determines the Efficacy of Glycosylation by Amylosucrase

JC Lee, SR Upadhyaya, SB Thapa, OJ Amoah… - 2024 - researchsquare.com
Flavonoids are multi-active ingredients found in most cosmetics and are used as
antioxidants and calming agents. They are plant-based naturally occurring pharmacological …