Plasma bile acid profile in patients with and without type 2 diabetes

A Mantovani, A Dalbeni, D Peserico, F Cattazzo… - Metabolites, 2021 - mdpi.com
A paucity of information currently exists on plasma bile acid (BA) profiles in patients with and
without type 2 diabetes mellitus (T2DM). We assayed 14 plasma BA species in 224 patients …

[HTML][HTML] Recent solid-phase microextraction-based analytical approaches for the profiling of biliary bile acids in pre-transplant assessments of liver grafts subjected to …

K Łuczykowski, N Warmuzińska, K Jaroch… - Analytica Chimica …, 2024 - Elsevier
Background Liver transplantation is the definitive treatment for end-stage liver failure, but the
scarcity of donor organs remains a significant challenge. Leveraging organs from extended …

Plasma bile acid profiling and modulation of secreted mucin 5AC in cholangiocarcinoma

E Danese, PMJ Lievens, A Padoan, D Peserico… - International Journal of …, 2023 - mdpi.com
Studies investigating the potential role of circulating bile acids (BAs) as diagnostic
biomarkers for cholangiocarcinoma (CCA) are sparse and existing data do not adjust for …

Explainable liver tumor delineation in surgical specimens using hyperspectral imaging and deep learning

Y Zhang, S Yu, X Zhu, X Ning, W Liu… - Biomedical optics …, 2021 - opg.optica.org
Surgical removal is the primary treatment for liver cancer, but frequent recurrence caused by
residual malignant tissue remains an important challenge, as recurrence leads to high …

Identification of Novel Biomarkers for Early Diagnosis of Atherosclerosis Using High-Resolution Metabolomics

SW Sardar, J Nam, TE Kim, H Kim, YH Park - Metabolites, 2023 - mdpi.com
Atherosclerosis (AS) is a metabolic disorder and the pre-stage of several cardiovascular
diseases, including myocardial infarction, stroke, and angina pectoris. Early detection of AS …

Targeted LC-MS/MS profiling of bile acids reveals primary/secondary bile acid ratio as a novel biomarker for necrotizing enterocolitis

T Gao, S Hu, W Xu, Z Wang, T Guo, F Chen… - Analytical and …, 2024 - Springer
Bile acids (BAs) are involved in the development of necrotizing enterocolitis (NEC), which
mainly occurs in preterm infants. We aim to identify the change of BAs in preterm infants and …

[HTML][HTML] Effects of dietary of bile acid on growth performance, antioxidant capacity, liver and intestinal health and immune function in loach (Misgurnus …

H Liu, X Zhang, K Li, Q Fang, X Liu, L Sun, G Guo… - Aquaculture …, 2024 - Elsevier
Bile acid (BA) play an important role in nutrient absorption and are key regulators of
antioxidant and immune response homeostasis. The purpose of this study was to evaluate …

Machine learning model comparison in the screening of cholangiocarcinoma using plasma bile acids profiles

D Negrini, P Zecchin, A Ruzzenente, F Bagante… - Diagnostics, 2020 - mdpi.com
Bile acids (BAs) assessments are garnering increasing interest for their potential
involvement in development and progression of cholangiocarcinoma (CCA). Since machine …

[HTML][HTML] Liquid Chromatography/Tandem Mass Spectrometry-Based Simultaneous Analysis of 32 Bile Acids in Plasma and Conventional Biomarker-Integrated …

M Yamauchi, M Maekawa, T Sato, Y Sato, M Kumondai… - Metabolites, 2024 - mdpi.com
Imaging tests, tumor marker (TM) screening, and biochemical tests provide a definitive
diagnosis of hepatocellular carcinoma (HCC). However, some patients with HCC may …

A novel approach to quantitative profiling of bile acids in dog blood serum by means triple quadruple LC-MS/MS: A step-by-step method optimization

K Lányi, DS Kiss, M Süth, K Németh, Á Sterczer - Microchemical Journal, 2024 - Elsevier
Background Although a considerable number of research was published about the analysis
of bile acids in the past decades, their quantitative determination from biological matrices is …