Vital internal organs display a left-right (LR) asymmetric arrangement that is established
during embryonic development. Disruption of this LR asymmetry—or laterality—can result in …

The majority of congenital cardiovascular disease including structural cardiac defects,
abnormalities in cardiac function, and rhythm disturbances can be identified prenatally using …

Background/Objectives: The failure of physiological left-right (LR) patterning, a critical
embryological process responsible for establishing the asymmetric positioning of internal …

Heterotaxy (HTX) is a group of clinical conditions with a shared pathology of dislocation of
one or more organs along the left–right axis. The etiology of HTX is tremendously …

Pregestational diabetes is a risk factor for congenital anomalies, including heterotaxy
syndrome, a rare birth defect characterized by the abnormal arrangement of organs relative …

Heterotaxy is a disorder characterized by severe congenital heart defects (CHDs) and
abnormal left-right patterning in other thoracic or abdominal organs. Clinical and research …

Heterotaxy syndrome is a complex condition caused by abnormal establishment of left-or
right-sidedness early in embryologic development. It affects the location and function of …

Errors in embryonic cardiac development are a leading cause of congenital heart defects
(CHDs), including morphological abnormalities of the heart that are often detected after birth …

Objective To report our recent experience with prenatal detection of significant
cardiovascular malformations (CVMs) in Nevada's state‐wide maternal population receiving …

Background Disordered lymphatic drainage is common in congenital heart diseases (CHD),
but thoracic duct (TD) drainage patterns in heterotaxy have not been described in detail …