The nuclear factor-κB (NF-κB) family of transcription factors plays a central part in the host
response to infection by microbial pathogens, by orchestrating the innate and acquired host …

MicroRNAs (miRNAs) are the subject of enormous interest. They are small non-coding
RNAs that play a regulatory role in numerous and diverse cellular processes such as …

The heterogeneous nature of tumour microenvironment (TME) underlying diverse treatment
responses remains unclear in nasopharyngeal carcinoma (NPC). Here, we profile 176,447 …

Epstein–Barr virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV), formally designated
human herpesvirus 4 (HHV-4) and 8 (HHV-8), respectively, are viruses that can cause a …

EZH2 is the catalytic subunit of the polycomb repressive complex 2 (PRC2), which along
with other PRC2 components mediates gene expression suppression via the methylation of …

Cancer progression begins when malignant cells colonize adjacent sites, and it is
characterized by increasing tumor heterogeneity, invasion and dissemination of cancer …

ABSTRACT A number of sentinels sense incoming herpes simplex virus (HSV) virions and
initiate an immediate innate response. The first line of defense at the cell surface is TLR2 …

Two lymphotropic human gamma herpesviruses can cause lymphoproliferative disorders:
Epstein Barr virus (EBV, formally designated as human herpesvirus 4) and Kaposi sarcoma …

Despite the introduction of highly active antiretroviral therapy or combination antiretroviral
therapy (HAART and cART, respectively) patients infected with HIV might develop certain …

Epstein-Barr virus (EBV) has developed effective strategies to evade host innate immune
responses. Here we reported on mitigation of type I interferon (IFN) production by EBV …