Natural selection in cancer biology: from molecular snowflakes to trait hallmarks

A Fortunato, A Boddy, D Mallo… - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Evolution by natural selection is the conceptual foundation for nearly every branch of biology
and increasingly also for biomedicine and medical research. In cancer biology, evolution …

LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations

Y Li, L Li, Z Wang, T Pan, N Sahni, X Jin… - Nucleic acids …, 2018 - academic.oup.com
Gene regulatory network perturbations contribute to the development and progression of
cancer, however, molecular determinants that mediate transcriptional perturbations remain a …

Long noncoding RNA NEAT1 promotes progression of glioma as a ceRNA by sponging miR‐185‐5p to stimulate DNMT1/mTOR signaling

H Yu, A Xu, B Wu, M Wang… - Journal of cellular …, 2021 - Wiley Online Library
Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) is regarded as an
oncogene in multiple cancers. Previous studies have shown that NEAT1 is involved in the …

Characterization of transcriptome transition associates long noncoding RNAs with glioma progression

X Lin, T Jiang, J Bai, J Li, T Wang, J Xiao, Y Tian… - … Therapy-Nucleic Acids, 2018 - cell.com
Long noncoding RNAs (lncRNAs) have been implicated in cancer biogenesis and
prognosis. However, we still lack knowledge on their function during glioma progression. In …

Shared molecular mechanisms between Alzheimer's disease and periodontitis revealed by transcriptomic analysis

J Jin, M Guang, AC Ogbuehi, S Li… - BioMed Research …, 2021 - Wiley Online Library
Objective. To investigate the genetic crosstalk mechanisms that link periodontitis and
Alzheimer's disease (AD). Background. Periodontitis, a common oral infectious disease, is …

Oncogenic landscape of somatic mutations perturbing pan-cancer lncRNA-ceRNA regulation

Y Zhang, P Han, Q Guo, Y Hao, Y Qi, M Xin… - Frontiers in Cell and …, 2021 - frontiersin.org
Competing endogenous RNAs (ceRNA) are transcripts that communicate with and co-
regulate each other by competing for the binding of shared microRNAs (miRNAs). Long non …

[HTML][HTML] Identification and characterization of lncRNA mediated transcriptional dysregulation dictates lncRNA roles in glioblastoma

Y Li, Z Wang, Y Wang, Z Zhao, J Zhang, J Lu, J Xu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) modulate gene expression, and lncRNA misregulation is
associated with cancer. However, precise functional roles in biological and disease …

A Transcription Factor ZNF384, Regulated by LINC00265, Activates the Expression of IFI30 to Stimulate Malignant Progression in Glioma

J Yang, S Yang, J Cai, H Chen, L Sun… - ACS Chemical …, 2023 - ACS Publications
Glioma remains one of the most challenging primary brain malignancies to treat. Long
noncoding RNAs (lncRNAs) and mRNAs (mRNAs) are implicated in regulating the …

Dynamic TF-lncRNA regulatory networks revealed prognostic signatures in the development of ovarian cancer

Q Guo, J Wang, Y Gao, X Li, Y Hao, S Ning… - … in bioengineering and …, 2020 - frontiersin.org
The pathological development of ovarian cancer (OC) is a complex progression that
depends on multiple alterations of coding and non-coding genes. Therefore, it is important to …

Effect of R-SO2-R′ ligands on the gold-based catalysts for acetylene hydrochlorination: A DFT study

J Yang, H Shen, X Yuan, J Zhao - Colloids and Surfaces A …, 2023 - Elsevier
Gold-based mercury-free catalysts have great potential in the industrial production of vinyl
chloride. In order to further understand the factors affecting the catalytic activity, the catalytic …