HS Krishnan, L Ma, N Vasdev… - Chemistry–A European …, 2017 - Wiley Online Library
Positron emission tomography (PET) imaging study of fluorine‐18 labeled biomolecules is an emerging and rapidly growing area for preclinical and clinical research. The present …
PY Keng, S Chen, H Ding, S Sadeghi… - Proceedings of the …, 2012 - National Acad Sciences
We have developed an all-electronic digital microfluidic device for microscale chemical synthesis in organic solvents, operated by electrowetting-on-dielectric (EWOD). As an …
The increased demand for molecular imaging tracers useful in assessing and monitoring diseases has stimulated research towards more efficient and flexible radiosynthetic routes …
C Rensch, A Jackson, S Lindner, R Salvamoser… - Molecules, 2013 - mdpi.com
Application of microfluidics to Positron Emission Tomography (PET) tracer synthesis has attracted increasing interest within the last decade. The technical advantages of …
LYF Haveman, DJ Vugts, AD Windhorst - EJNMMI Radiopharmacy and …, 2023 - Springer
Background Positron emission tomography (PET) is a powerful, non-invasive preclinical and clinical nuclear imaging technique used in disease diagnosis and therapy assessment …
H Mallapura, L Tanguy, B Långström, LL Meunier… - Molecules, 2022 - mdpi.com
In the last decade, microfluidic techniques have been explored in radiochemistry, and some of them have been implemented in preclinical production. However, these are not suitable …
K Kumar, A Ghosh - Bioconjugate chemistry, 2018 - ACS Publications
The clinical applications of positron emission tomography (PET) imaging pharmaceuticals have increased tremendously over the past several years since the approval of 18fluorine …
PY Keng, RM van Dam - Molecular imaging, 2015 - journals.sagepub.com
The emerging technology of digital microfluidics is opening up the possibility of performing radiochemistry at the microliter scale to produce tracers for positron emission tomography …
Application of microfluidics offers numerous advantages in the field of radiochemistry and could enable dramatic reductions in the cost of producing radiotracers for positron emission …