Replacing in vivo with in vitro studies can increase sustainability in the development of
medicines. This principle has already been applied in the biowaiver approach based on the …

Purpose The current study aimed to discuss the potential of nanospanlastics as a surfactant-
based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic …

The search for small molecule inhibitors has gained prominence with the recognition of their
inherent advantage for cancer therapy. Combretastatin is a naturally occurring small …

Quercetin, a flavonoid with possible neuroprotective action has been recently suggested for
the early-stage treatment of Alzheimer's disease. The low solubility and extended first pass …

Mutations on the epidermal growth factor receptor (EGFR), induction of angiogenesis, and
reprogramming cellular energetics are all biological features acquired by tumor cells during …

Hydrogels are an attractive platform for drug delivery to the skin. Current cellulose hydrogel
developments commonly focus on readily available bleached woody cellulose. Considering …

Several therapeutically active molecules are poorly water-soluble, thereby creating a
challenge for pharmaceutical scientists to develop an active solution for their oral drug …

In this work, metal-organic frameworks on the basis of γ-cyclodextrin (γCD-MOF) were
proposed as carriers for methotrexate (MTX) which is widely used as chemotherapy agent …

Subcutaneous (subQ) injection is a common route for delivering biotherapeutics, wherein
pharmacokinetics is largely influenced by drug transport in a complex subQ tissue …

The association of alginate beads and guar-gum films in a single delivery system was
idealized to promote a more effective buccal and oral delivery of bioactive molecules. A …