Preeclampsia—Pathophysiology and Clinical Presentations: JACC State-of-the-Art Review

CW Ives, R Sinkey, I Rajapreyar, ATN Tita… - Journal of the American …, 2020 - jacc.org
Preeclampsia is a hypertensive disorder of pregnancy. It affects 2% to 8% of pregnancies
worldwide and causes significant maternal and perinatal morbidity and mortality …

Preeclampsia and eclampsia: the conceptual evolution of a syndrome

O Erez, R Romero, E Jung, P Chaemsaithong… - American journal of …, 2022 - Elsevier
Preeclampsia, one of the most enigmatic complications of pregnancy, is considered a
pregnancy-specific disorder caused by the placenta and cured only by delivery. This article …

Sex differences in heart failure

CSP Lam, C Arnott, AL Beale… - European heart …, 2019 - academic.oup.com
The overall lifetime risk of heart failure (HF) is similar between men and women, however,
there are marked sex differences in the landscape of this condition that are both important …

Preeclampsia: pathophysiology, challenges, and perspectives

S Rana, E Lemoine, JP Granger… - Circulation …, 2019 - Am Heart Assoc
Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Fundamental mechanisms of regulated cell death and implications for heart disease

DP Del Re, D Amgalan, A Linkermann… - Physiological …, 2019 - journals.physiology.org
Twelve regulated cell death programs have been described. We review in detail the basic
biology of nine including death receptor-mediated apoptosis, death receptor-mediated …

Pre-eclampsia: pathogenesis, novel diagnostics and therapies

EA Phipps, R Thadhani, T Benzing… - Nature Reviews …, 2019 - nature.com
Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …

Mechanisms of physiological and pathological cardiac hypertrophy

M Nakamura, J Sadoshima - Nature Reviews Cardiology, 2018 - nature.com
Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders

S Rana, SD Burke, SA Karumanchi - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Pathophysiology, diagnosis and management of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of …

J Bauersachs, T König, P van der Meer… - European journal of …, 2019 - Wiley Online Library
Peripartum cardiomyopathy (PPCM) is a potentially life‐threatening condition typically
presenting as heart failure with reduced ejection fraction (HFrEF) in the last month of …

Peripartum Cardiomyopathy: JACC State-of-the-Art Review

MB Davis, Z Arany, DM McNamara, S Goland… - Journal of the American …, 2020 - jacc.org
Peripartum cardiomyopathy is a form of systolic heart failure affecting young women toward
the end of pregnancy or in the months following delivery. Incidence is higher in African …