Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments

SN Lone, S Nisar, T Masoodi, M Singh, A Rizwan… - Molecular cancer, 2022 - Springer
Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly
being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have …

Liquid biopsy of cancer: a multimodal diagnostic tool in clinical oncology

R Palmirotta, D Lovero, P Cafforio… - … in medical oncology, 2018 - journals.sagepub.com
Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …

Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment

M Marzagalli, ND Ebelt, ER Manuel - Seminars in cancer biology, 2019 - Elsevier
Cutaneous melanoma is the most common skin cancer with an incidence that has been
rapidly increasing in the past decades. Melanomas are among the most immunogenic …

The role of exosomes and their applications in cancer

Y Zhou, Y Zhang, H Gong, S Luo, Y Cui - International journal of …, 2021 - mdpi.com
Exosomes are very small extracellular vesicles secreted by multiple cell types and are
extensively distributed in various biological fluids. Recent research indicated that exosomes …

Non-melanoma skin cancers: Biological and clinical features

M Cives, F Mannavola, L Lospalluti, MC Sergi… - International Journal of …, 2020 - mdpi.com
Non-melanoma skin cancers (NMSCs) include basal cell carcinoma (BCC), squamous cell
carcinoma (SCC) and Merkel cell carcinoma (MCC). These neoplasms are highly diverse in …

The influence of tumor microenvironment on immune escape of melanoma

A Simiczyjew, E Dratkiewicz, J Mazurkiewicz… - International Journal of …, 2020 - mdpi.com
The low efficiency of currently-used anti-cancer therapies poses a serious challenge,
especially in the case of malignant melanoma, a cancer characterized by elevated …

Tumor microenvironment: Interactions and therapy

M Najafi, NH Goradel, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
Tumor microenvironment (TME) is a host for a complex network of heterogeneous stromal
cells with overlapping or opposing functions depending on the dominant signals within this …

Communication in the cancer microenvironment as a target for therapeutic interventions

A Dominiak, B Chełstowska, W Olejarz, G Nowicka - Cancers, 2020 - mdpi.com
The tumor microenvironment (TME) is a complex system composed of multiple cells, such as
non-cancerous fibroblasts, adipocytes, immune and vascular cells, as well as signal …

Immune system evasion as hallmark of melanoma progression: the role of dendritic cells

M Tucci, A Passarelli, F Mannavola, C Felici… - Frontiers in …, 2019 - frontiersin.org
Melanoma is an immunogenic tumor whose relationship with immune cells resident in the
microenvironment significantly influences cancer cell proliferation, progression, and …

Exosomes: Current use and future applications

IM Chung, G Rajakumar, B Venkidasamy… - Clinica Chimica …, 2020 - Elsevier
Exosomes are endosomal-derived vesicles that play a critical role in cell-to-cell
communication and are secreted in several biological fluids including serum, saliva, urine …