Consensus on the monitoring, treatment, and prevention of leukaemia relapse after allogeneic haematopoietic stem cell transplantation in China: 2024 update

Y Wang, YJ Chang, J Chen, M Han, JD Hu, J Hu… - Cancer Letters, 2024 - Elsevier
The consensus in 2018 from The Chinese Society of Haematology (CSH) on the monitoring,
treatment, and prevention of leukaemia relapse after allogeneic haematopoietic stem cell …

Switching from salvage chemotherapy to immunotherapy in adult B-cell acute lymphoblastic leukemia

D Kegyes, C Jitaru, G Ghiaur, S Ciurea, D Hoelzer… - Blood Reviews, 2023 - Elsevier
About one-half of adults with acute B-cell lymphoblastic leukemia (B-ALL) who do not
achieve molecular complete remission or who subsequently relapse are not cured by …

Analysis benefits of a second allo-HSCT after CAR-T cell therapy in patients with relapsed/refractory B-cell acute lymphoblastic leukemia who relapsed after transplant

X Cao, J Zhang, Y Zhao, M Xiong, J Zhou, Y Lu… - Frontiers in …, 2023 - frontiersin.org
Background Chimeric antigen receptor (CAR) T-cell therapy has demonstrated high initial
complete remission (CR) rates in B-cell acute lymphoblastic leukemia (B-ALL) patients …

Combining blinatumomab and donor lymphocyte infusion in B-ALL patients relapsing after allogeneic hematopoietic cell transplantation: a study of the SFGM-TC

P Chauvet, A Paviglianiti, M Labopin… - Bone marrow …, 2023 - nature.com
Relapsed B-cell acute lymphoblastic leukemia (B-ALL) after allogeneic stem cell
transplantation (allo-HCT) still represents a major concern with poor outcomes. The aim of …

Efficacy and safety of CD19 CAR-T cell therapy for acute lymphoblastic leukemia patients relapsed after allogeneic hematopoietic stem cell transplantation

X Cao, J Li, P Lu, K Liu - International Journal of Hematology, 2022 - Springer
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective therapy for B-
cell acute lymphoblastic leukemia (B-ALL). Although allo-HSCT can be curative for some B …

Post-Hematopoietic Cell Transplantation Relapsed Acute Lymphoblastic Leukemia: Current Challenges and Future Directions

I Varadarajan, E Pierce, L Scheuing… - OncoTargets and …, 2023 - Taylor & Francis
Allogeneic hematopoietic cell transplantation (allo-HCT) represents an important and
potentially curative treatment option for adult patients with acute lymphoblastic leukemia …

Immune Therapies of B-cell Acute Lymphoblastic Leukaemia in Children and Adults

D Kegyes, G Ghiaur, A Bancos, C Tomuleasa… - Critical Reviews in …, 2024 - Elsevier
ABSTRACT B-cell acute lymphoblastic leukaemia (B-cell ALL) is a common haematologic
cancer in children and adults. About 10 percent of children and 50 percent of adults fail to …

Novel mechanism and strategies to overcome relapse after allogeneic stem cell transplantation

Y Sun, X Zhang, L Hu, MB Abid - Frontiers in Immunology, 2023 - frontiersin.org
The curative potential of allogeneic hematopoietic stem cell transplant (allo-HCT) for
hematologic malignancies and nonmalignant conditions was first explored during the 1950s …

Bispecific Antibodies and Other Non-CAR Targeted Therapies and HSCT: Decreased Toxicity for Better Transplant Outcome in Paediatric ALL?

KM Kállay, M Algeri, J Buechner, AC Krauss - Frontiers in Pediatrics, 2022 - frontiersin.org
This review will address the place of innovative, non-chemotherapy, non-CAR-T targeted
therapies in the treatment of Acute Lymphoblastic Leukaemia (ALL), focusing on their use in …

[HTML][HTML] Preemptive inotuzumab ozogamicin eradicated measurable residual disease in Ph‐negative acute lymphoblastic leukemia relapsed post CD19 CART …

SM Huang, CL Wan, HY Cao, YY Li, CS Qian… - Clinical Case …, 2023 - ncbi.nlm.nih.gov
The prognosis of adult relapse or refractory B-cell acute lymphoblastic leukemia (r/r B-ALL)
is dismal, with a complete remission rate of approximately 18%–44% if receiving salvage …