The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Messenger ribonucleic acid (mRNA)-based drugs, notably mRNA vaccines, have been
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …

RNA-based therapies, including RNA molecules as drugs and RNA-targeted small
molecules, offer unique opportunities to expand the range of therapeutic targets. Various …

Vaccination represents the best line of defense against infectious diseases and is crucial in
curtailing pandemic spread of emerging pathogens to which a population has limited …

The first therapeutic nucleic acid, a DNA oligonucleotide, was approved for clinical use in
1998. Twenty years later, in 2018, the first therapeutic RNA-based oligonucleotide was …

Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …

In recent years, messenger RNA (mRNA) has come into the spotlight as a versatile
therapeutic with the potential to prevent and treat a staggering range of diseases. Billions of …

In the early nineties, pioneering steps were taken in the use of mRNA as a therapeutic tool
for vaccination. In the following decades, an improved understanding of the mRNA …

Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …

With the rapid success in the development of mRNA vaccines against COVID-19 and with a
number of mRNA-based drugs ahead in the pipelines, mRNA has catapulted to the forefront …