Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology

A Khoruts, C Staley, MJ Sadowsky - Nature Reviews Gastroenterology & …, 2021 - nature.com
Faecal microbiota transplantation (FMT) has emerged as a remarkably successful treatment
for recurrent Clostridioides difficile infection that cannot be cured with antibiotics alone …

Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for …

LC McDonald, DN Gerding, S Johnson… - Clinical infectious …, 2018 - academic.oup.com
Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Host immunity and immunization strategies for Clostridioides difficile infection

F Naz, WA Petri - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Clostridioides difficile infection (CDI) represents a significant challenge to public health. C.
difficile-associated mortality and morbidity have led the US CDC to designate it as an urgent …

Clostridium difficile infection: an epidemiology update

AC De Roo, SE Regenbogen - Clinics in colon and rectal …, 2020 - thieme-connect.com
Clostridium (reclassified as “Clostridioides”) difficile infection (CDI) is a healthcare-
associated infection and significant source of potentially preventable morbidity, recurrence …

New insights in Coxiella burnetii infection: diagnosis and therapeutic update

C Melenotte, M Million, D Raoult - Expert review of anti-infective …, 2020 - Taylor & Francis
Introduction: Coxiella burnetii infection is still challenging physicians, mainly because no
international coordination has been stated to standardize the therapeutic strategy and …

[HTML][HTML] Management of Clostridium difficile infection

LS Al-Jashaami, HL DuPont - Gastroenterology & hepatology, 2016 - ncbi.nlm.nih.gov
Since the discovery of Clostridium difficile infection (CDI) in the 1970s, there has been an
increase in the incidence, severity, and recurrence rate of the disease. We reviewed the …

The microbiota and immune response during Clostridium difficile infection

EL Buonomo, WA Petri Jr - Anaerobe, 2016 - Elsevier
Clostridium difficile is a gram-positive, spore forming anaerobe that infects the gut when the
normal microbiota has been disrupted. C. difficile infection (CDI) is the most common cause …

Older Is Not Wiser, Immunologically Speaking: Effect of Aging on Host Response to Clostridium difficile Infections

JH Shin, KP High, CA Warren - Journals of Gerontology Series A …, 2016 - academic.oup.com
Clostridium difficile infection (CDI) is the most common cause of antibiotic-associated
diarrhea and a significant burden on the health care system. Aging has been identified in the …

Clostridioides difficile infections; new treatments and future perspectives

C Normington, CH Chilton… - Current Opinion in …, 2024 - journals.lww.com
With current first-in-line antibiotic therapy options associated with high levels of recurrent
CDI, the availability of new generation targeted therapeutics can really impact treatment …