The most commonly used modern anthelmintics include the benzimidazoles, the nicotinic
agonists, praziquantel, triclabendazole and the macrocyclic lactones. These drugs interfere …

Praziquantel is the drug of choice for the treatment of all forms of schistosomiasis. This
review summarizes the main features of the drug, with special attention being given to those …

Schistosoma mansoni infections in mice were treated with subcurative multiple doses of
either praziquantel (PZQ) or oxamniquine (OX). With an early exception, the drug treatments …

The efficacy of praziquantel against a Puerto Rican strain of Schistosoma mansoni was
assessed using both in vivo and in vitro approach. The drug effective dose (50%) in the …

Helminth infections are an important constraint on the health and development of poor
children and adults. Anthelmintic treatment programmes provide a safe and effective …

The major antischistosomal drugs that have been or still are in use against infections with
schistosomes are considered here together with some compounds that have not been in …

The anthelmintic drug praziquantel (PZQ) is used to treat schistosomiasis, a neglected
tropical disease that affects over 200 million people worldwide. PZQ causes Ca 2+ influx …

There is a recent report of low efficacy of praziquantel (PZQ) treatment of human
schistosomiasis in a new Schistosoma mansoni focus in northern Senegal. Biomphalaria …

Infectious diseases caused by parasites are a major threat for the entire mankind, especially
in the tropics. More than 1 billion people world-wide are directly exposed to tropical …

Infections with parasitic helminths and protozoa are important causes of morbidity and
mortality worldwide. Chemotherapy has an important role not only in the treatment of …