Pathophysiology, diagnosis, and management of endometriosis

AW Horne, SA Missmer - bmj, 2022 - bmj.com
Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

[HTML][HTML] Endometriosis-associated infertility: From pathophysiology to tailored treatment

G Bonavina, HS Taylor - Frontiers in endocrinology, 2022 - frontiersin.org
Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

[HTML][HTML] Menstruation: science and society

HOD Critchley, E Babayev, SE Bulun, S Clark… - American journal of …, 2020 - Elsevier
Women's health concerns are generally underrepresented in basic and translational
research, but reproductive health in particular has been hampered by a lack of …

[HTML][HTML] Physiology of the endometrium and regulation of menstruation

HOD Critchley, JA Maybin… - Physiological …, 2020 - journals.physiology.org
The physiological functions of the uterine endometrium (uterine lining) are preparation for
implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …

The origin and pathogenesis of endometriosis

Y Wang, K Nicholes, IM Shih - Annual Review of Pathology …, 2020 - annualreviews.org
Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …

Endometriosis: epidemiology, diagnosis and clinical management

P Parasar, P Ozcan, KL Terry - Current obstetrics and gynecology reports, 2017 - Springer
Abstract Purpose of Review Endometriosis is a disease of adolescents and reproductive-
aged women characterized by the presence of endometrial tissue outside the uterine cavity …

Endometrial decidualization: the primary driver of pregnancy health

SW Ng, GA Norwitz, M Pavlicev, T Tilburgs… - International journal of …, 2020 - mdpi.com
Interventions to prevent pregnancy complications have been largely unsuccessful. We
suggest this is because the foundation for a healthy pregnancy is laid prior to the …

[HTML][HTML] Pathogenesis of endometriosis: the genetic/epigenetic theory

PR Koninckx, A Ussia, L Adamyan, A Wattiez… - Fertility and sterility, 2019 - Elsevier
Objective To study the pathophysiology of endometriosis. Design Overview of observations
on endometriosis. Setting Not applicable. Patient (s) None. Interventions (s) None. Main …

Treatment of endometriosis-associated pain with elagolix, an oral GnRH antagonist

HS Taylor, LC Giudice, BA Lessey… - … England Journal of …, 2017 - Mass Medical Soc
Background Endometriosis is a chronic, estrogen-dependent condition that causes
dysmenorrhea and pelvic pain. Elagolix, an oral, nonpeptide, gonadotropin-releasing …