S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

Our immune system is based on the close collaboration of the innate and adaptive immune
systems for the rapid detection of any threats to the host. Recognition of pathogen-derived …

Neutrophils and monocytes belong to the first line of immune defence cells and are recruited
to sites of inflammation during infection or sterile injury. Both cells contain huge amounts of …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Abstract Background Calprotectin (S100A8/S100A9), a heterodimeric EF-hand Ca 2+
binding protein, are abundant in cytosol of neutrophils and are involved in inflammatory …

The receptor for advanced glycation end products (RAGE) is a central signaling molecule in
the innate immune system and is involved in the onset and sustainment of the inflammatory …

The innate immune system forms the first line of protection against infectious and non-
infectious tissue injury. Cells of the innate immune system detect pathogen-associated …

J. Neurochem.(2012) 120, 644–659. Abstract S100B is a calcium‐binding protein
concentrated in glial cells, although it has also been detected in definite extra‐neural cell …