Clinical applications of near-infrared diffuse correlation spectroscopy and tomography for tissue blood flow monitoring and imaging

Y Shang, T Li, G Yu - Physiological measurement, 2017 - iopscience.iop.org
Objective. Blood flow is one such available observable promoting a wealth of physiological
insight both individually and in combination with other metrics. Approach. Near-infrared …

Multi-speckle diffuse correlation spectroscopy to measure cerebral blood flow

K Murali, HM Varma - Biomedical optics express, 2020 - opg.optica.org
We present a multi-speckle diffuse correlation spectroscopy (DCS) system for measuring
cerebral blood flow in the healthy adult human brain. In contrast to the need for a high frame …

A wearable fiberless optical sensor for continuous monitoring of cerebral blood flow in mice

C Huang, Y Gu, J Chen, AA Bahrani… - IEEE Journal of …, 2018 - ieeexplore.ieee.org
Continuous and longitudinal monitoring of cerebral blood flow (CBF) in animal models
provides information for studying the mechanisms and interventions of various cerebral …

High-density diffuse correlation tomography with enhanced depth localization and minimal surface artefacts

R Paul, K Murali, HM Varma - Biomedical optics express, 2022 - opg.optica.org
A spatially weighted filter applied to both the measurement and the Jacobian is proposed for
high-density diffuse correlation tomography (DCT) to remove unwanted extracerebral …

Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision

L Cortese, G Lo Presti, M Pagliazzi… - Biomedical Optics …, 2021 - opg.optica.org
Over the recent years, a typical implementation of diffuse correlation spectroscopy (DCS)
instrumentation has been adapted widely. However, there are no detailed and accepted …

Simultaneous measurements of tissue blood flow and oxygenation using a wearable fiber-free optical sensor

X Liu, Y Gu, C Huang, M Zhao, Y Cheng… - Journal of …, 2021 - spiedigitallibrary.org
Significance: There is an essential need to develop wearable multimodality technologies
that can continuously measure both blood flow and oxygenation in deep tissues to …

Recovery of the diffuse correlation spectroscopy data-type from speckle contrast measurements: towards low-cost, deep-tissue blood flow measurements

K Murali, AK Nandakumaran, T Durduran… - Biomedical optics …, 2019 - opg.optica.org
A multi-step Volterra integral equation-based algorithm was developed to measure the
electric field auto-correlation function from multi-exposure speckle contrast data. This …

Noncontact 3-D speckle contrast diffuse correlation tomography of tissue blood flow distribution

C Huang, D Irwin, M Zhao, Y Shang… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Recent advancements in near-infrared diffuse correlation techniques and instrumentation
have opened the path for versatile deep tissue microvasculature blood flow imaging …

Intraoperative optical and fluorescence imaging of blood flow distributions in mastectomy skin flaps for identifying ischemic tissues

S Mazdeyasna, C Huang, AB Paranzino… - Plastic and …, 2022 - journals.lww.com
Insufficient blood flow causes mastectomy skin flap necrosis in 5 to 30 percent of cases.
Fluorescence angiography with the injection of indocyanine green dye has shown high …

Time-resolved laser speckle contrast imaging (TR-LSCI) of cerebral blood flow

F Fathi, S Mazdeyasna, D Singh, C Huang… - arXiv preprint arXiv …, 2023 - arxiv.org
To address many of the deficiencies in optical neuroimaging technologies such as poor
spatial resolution, time-consuming reconstruction, low penetration depth, and contact-based …