[HTML][HTML] Endothelial glycocalyx

CA Foote, RN Soares, FI Ramirez-Perez… - Comprehensive …, 2022 - ncbi.nlm.nih.gov
The glycocalyx is a polysaccharide structure that protrudes from the body of a cell. It is
primarily conformed of glycoproteins and proteoglycans, which provide communication …

[HTML][HTML] Physiological functions of the cholinergic system in immune cells

T Fujii, M Mashimo, Y Moriwaki, H Misawa… - Journal of …, 2017 - Elsevier
T and B cells, macrophages and dendritic cells (DCs) all express most of the components
necessary for a functional cholinergic system. This includes choline acetyltransferase …

The molecular heterogeneity of store-operated Ca2+ entry in vascular endothelial cells: the different roles of Orai1 and TRPC1/TRPC4 channels in the transition from …

F Moccia, V Brunetti, A Perna, G Guerra… - International journal of …, 2023 - mdpi.com
Store-operated Ca2+ entry (SOCE) is activated in response to the inositol-1, 4, 5-
trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …

Acetylcholine signaling system in progression of lung cancers

JR Friedman, SD Richbart, JC Merritt, KC Brown… - Pharmacology & …, 2019 - Elsevier
The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung
cancer. Several lines of evidence show that lung cancer cells express all of the proteins …

Increased vascular contractility in hypertension results from impaired endothelial calcium signaling

C Wilson, X Zhang, C Buckley, HR Heathcote… - …, 2019 - Am Heart Assoc
Endothelial cells line all blood vessels and are critical regulators of vascular tone. In
hypertension, disruption of endothelial function alters the release of endothelial-derived …

Coronary microvascular disease in contemporary clinical practice

NR Smilowitz, O Toleva, A Chieffo… - Circulation …, 2023 - Am Heart Assoc
Coronary microvascular disease (CMD) causes myocardial ischemia in a variety of clinical
scenarios. Clinical practice guidelines support routine testing for CMD in patients with …

Sympathetic and sensory-motor nerves in peripheral small arteries

C Aalkjær, H Nilsson, JGR De Mey - Physiological reviews, 2021 - journals.physiology.org
Small arteries, which play important roles in controlling blood flow, blood pressure, and
capillary pressure, are under nervous influence. Their innervation is predominantly …

The endothelium solves problems that endothelial cells do not know exist

JG McCarron, MD Lee, C Wilson - Trends in pharmacological sciences, 2017 - cell.com
The endothelium is the single layer of cells that lines the entire cardiovascular system and
regulates vascular tone and blood–tissue exchange, recruits blood cells, modulates blood …

Small-world connectivity dictates collective endothelial cell signaling

MD Lee, C Buckley, X Zhang… - Proceedings of the …, 2022 - National Acad Sciences
Every blood vessel is lined by a single layer of highly specialized, yet adaptable and
multifunctional endothelial cells. These cells, the endothelium, control vascular contractility …

Evidence for improved systemic and local vascular function after long‐term passive static stretching training of the musculoskeletal system

AV Bisconti, E Cè, S Longo, M Venturelli… - The Journal of …, 2020 - Wiley Online Library
Key points Vascular function and arterial stiffness are important markers of cardiovascular
health and cardiovascular co‐morbidity. Transitional phases of hypoemia and hypermia …