T Fujii, M Mashimo, Y Moriwaki, H Misawa… - Journal of …, 2017 - Elsevier
T and B cells, macrophages and dendritic cells (DCs) all express most of the components necessary for a functional cholinergic system. This includes choline acetyltransferase …
F Moccia, V Brunetti, A Perna, G Guerra… - International journal of …, 2023 - mdpi.com
Store-operated Ca2+ entry (SOCE) is activated in response to the inositol-1, 4, 5- trisphosphate (InsP3)-dependent depletion of the endoplasmic reticulum (ER) Ca2+ store …
The neurotransmitter acetylcholine (ACh) acts as an autocrine growth factor for human lung cancer. Several lines of evidence show that lung cancer cells express all of the proteins …
Endothelial cells line all blood vessels and are critical regulators of vascular tone. In hypertension, disruption of endothelial function alters the release of endothelial-derived …
NR Smilowitz, O Toleva, A Chieffo… - Circulation …, 2023 - Am Heart Assoc
Coronary microvascular disease (CMD) causes myocardial ischemia in a variety of clinical scenarios. Clinical practice guidelines support routine testing for CMD in patients with …
C Aalkjær, H Nilsson, JGR De Mey - Physiological reviews, 2021 - journals.physiology.org
Small arteries, which play important roles in controlling blood flow, blood pressure, and capillary pressure, are under nervous influence. Their innervation is predominantly …
JG McCarron, MD Lee, C Wilson - Trends in pharmacological sciences, 2017 - cell.com
The endothelium is the single layer of cells that lines the entire cardiovascular system and regulates vascular tone and blood–tissue exchange, recruits blood cells, modulates blood …
Every blood vessel is lined by a single layer of highly specialized, yet adaptable and multifunctional endothelial cells. These cells, the endothelium, control vascular contractility …
Key points Vascular function and arterial stiffness are important markers of cardiovascular health and cardiovascular co‐morbidity. Transitional phases of hypoemia and hypermia …