Allergic diseases, including atopic dermatitis, allergic rhinitis, asthma, and food allergy, are
caused by abnormal responses to relatively harmless foreign proteins called allergens …

The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral
environments remain mostly undefined. We show that differentiation of CD11blo migratory …

The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic
resistance create a global health concern. The challenge lies in the unique Gram-negative …

The relationship between the extrinsic environment and the internal transcriptional network
is circular. Naive T cells first engage with antigen‐presenting cells to set transcriptional …

Bone fractures, the most common musculoskeletal injuries, heal through three main phases:
inflammatory, repair, and remodeling. Around 10% of fracture patients suffer from impaired …

T helper 2 (Th2) responses protect against pathogens while also driving allergic
inflammation, yet how large-scale Th2 responses are generated in tissue context remains …

Co-localization of antigens and immunomodulators in the same antigen-presenting cells
(APCs) can powerfully activate APCs and enhance immune responses. In this study, the …

Antigen‐presenting cells (APCs) are critical cells bridging innate and adaptive immune
responses by taking up, processing, and presenting antigens to naïve T cells. At steady …

Immune responses must be rapid, tightly orchestrated, and tailored to the encountered
stimulus. Lymphatic vessels facilitate this process by continuously collecting immunological …

A vaccine must be sufficiently stable and cause no discernible discomfort or organ damage
both during administration and at the injection site. To achieve these aims, the skin offers a …