Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of
the gastrointestinal tract. They are potentially malignant, and have an unpredictable …

Simple Summary Most gastrointestinal stromal tumors (GISTs) arise due to gain-of-function
mutations of KIT and PDGFRA, encoding the receptor tyrosine kinase (RTK). The …

The discovery of activated KIT mutations in gastrointestinal (GI) stromal tumors (GISTs) in
1998 triggered a sea change in our understanding of these tumors and has ushered in a …

In recent years, the interstitial cells telocytes, formerly known as interstitial Cajal-like cells,
have been described in almost all organs of the human body. Although telocytes were …

Traditional genetic testing for patients with gastrointestinal stromal tumors (GISTs) focus on
those with syndromic features. To assess whether expanded genetic testing of GIST patients …

Gastrointestinal stromal tumors (GISTs) originate from interstitial cells of Cajal and account
for over 5,000 newly diagnosed cases in the United States. The discovery of activated KIT …

Abstract The Japan Society of Clinical Oncology Clinical Practice Guidelines 2022 for
gastrointestinal stromal tumor (GIST) have been published in accordance with the Minds …

Background: Gastrointestinal Stromal Tumors (GISTs) are characterized as round, well–
defined mass lesions in the submucosal layer of the gastrointestinal (GI) tract. GISTs often …

Simple Summary This systematic review of the medical literature concerning the overlap
between adnexal and gastrointestinal stromal tumors (GISTs) was designed to provide the …

Gastrointestinal stromal tumor (GIST) is the most common human sarcoma and usually
results from a sporadic mutation in KIT or, less frequently, platelet-derived growth factor …