Natural polymeric scaffolds can be used for tissue engineering applications such as cell
delivery and cell-free supporting of native tissues. This is because of their desirable …

Regenerating chondral and osteochondral injuries is a main challenge in orthopedics.
Some therapeutic strategies such as joint preservation operations, non-operative …

Over the past decades, numerous tissue-engineered constructs have been investigated for
the osteochondral repair. However, it still remains a challenge to regenerate the …

Tendon tissue connects muscle to bone and plays crucial roles in stress transfer. Tendon
injury remains a significant clinical challenge due to its complicated biological structure and …

Regenerative engineering holds the potential to treat clinically pervasive osteochondral
defects (OCDs). In a synthetic materials-guided approach, the scaffold's chemical and …

Tissue engineered constructs have the potential to function as in vitro pre-clinical models of
normal tissue function and disease pathogenesis for drug screening and toxicity …

Tissue engineering and regenerative medicine (TERM) has caused a revolution in present
and future trends of medicine and surgery. In different tissues, advanced TERM approaches …

In the past few years, great progress has been made to validate tissue engineering
strategies in preclinical studies and clinical trials on the regeneration of osteochondral …

Osteochondral lesions treatment and regeneration demands biomimetic strategies aiming
physicochemical and biological properties of both bone and cartilage tissues, with long-term …

For the last two decades, silk has been extensively used as scaffolds in tissue engineering
because of its remarkable properties. Unfortunately, the aneural property of cartilage limits …