Dissecting redox biology using fluorescent protein sensors

M Schwarzländer, TP Dick, AJ Meyer… - Antioxidants & redox …, 2016 - liebertpub.com
Significance: Fluorescent protein sensors have revitalized the field of redox biology by
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …

Cysteine and resistance to oxidative stress: implications for virulence and antibiotic resistance

A Tikhomirova, MM Rahman, SP Kidd, RL Ferrero… - Trends in …, 2024 - cell.com
Reactive oxygen species (ROS), including the superoxide radical anion (O 2•–), hydrogen
peroxide (H 2 O 2), and the hydroxyl radical (• HO), are inherent components of bacterial …

Microbiota mediated plasticity promotes thermal adaptation in the sea anemone Nematostella vectensis

L Baldassarre, H Ying, AM Reitzel… - Nature …, 2022 - nature.com
At the current rate of climate change, it is unlikely that multicellular organisms will be able to
adapt to changing environmental conditions through genetic recombination and natural …

Subversion of host recognition and defense systems by Francisella spp

CL Jones, BA Napier, TR Sampson… - Microbiology and …, 2012 - Am Soc Microbiol
Francisella tularensis is a Gram-negative intracellular pathogen and the causative agent of
the disease tularemia. Inhalation of as few as 10 bacteria is sufficient to cause severe …

Innate immune recognition: an issue more complex than expected

K Kubelkova, A Macela - Frontiers in cellular and infection …, 2019 - frontiersin.org
Primary interaction of an intracellular bacterium with its host cell is initiated by activation of
multiple signaling pathways in response to bacterium recognition itself or as cellular …

Bacterial Transition Metal P1B-ATPases: Transport Mechanism and Roles in Virulence

JM Argüello, M González-Guerrero, D Raimunda - Biochemistry, 2011 - ACS Publications
P1B-type ATPases are polytopic membrane proteins that couple the hydrolysis of ATP to the
efflux of cytoplasmic transition metals. This paper reviews recent progress in our …

Immunity to Francisella

SC Cowley, KL Elkins - Frontiers in microbiology, 2011 - frontiersin.org
In recent years, studies on the intracellular pathogen Francisella tularensis have greatly
intensified, generating a wealth of new information on the interaction of this organism with …

Metal manipulators and regulators in human pathogens: A comprehensive review on microbial redox copper metalloenzymes “multicopper oxidases and superoxide …

KK Sharma, D Singh, SV Mohite, PR Williamson… - International Journal of …, 2023 - Elsevier
The chemistry of metal ions with human pathogens is essential for their survival, energy
generation, redox signaling, and niche dominance. To regulate and manipulate the metal …

Evasion of host antioxidative response via disruption of NRF2 signaling in fatal Ehrlichia-induced liver injury

AK Sharma, A El Andaloussi, N Ismail - Plos Pathogens, 2023 - journals.plos.org
Ehrlichia is Gram negative obligate intracellular bacterium that cause human monocytotropic
ehrlichiosis (HME). HME is characterized by acute liver damage and inflammation that may …

Francisella tularensis subsp. holarctica Releases Differentially Loaded Outer Membrane Vesicles Under Various Stress Conditions

J Klimentova, I Pavkova, L Horcickova… - Frontiers in …, 2019 - frontiersin.org
Francisella tularensis is a Gram-negative, facultative intracellular bacterium, causing a
severe disease called tularemia. It secretes unusually shaped nanotubular outer membrane …