Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a
significant assembly motif for the development of new drug entities. Quinoline and its …

α, β-Unsaturated chalcone moieties and quinoline scaffolds play an important role in
medicinal chemistry, especially in the identification and development of potential anticancer …

Quinoline is an efficient scaffold for anticancer drug development as its derivatives have
shown potent results through several mechanisms like growth regulators through “apoptosis …

Novel imidazole-chalcone derivatives were designed and synthesized as tubulin
polymerization inhibitors and anticancer agents. The antiproliferative activity of the imidazole …

A new series of quinoline-chalcone hybrids was synthesized. The structures of these
compounds were characterized by spectroscopic methods including 1 H and 13 CNMR and …

Quinoline heterocycles have been considered important structures due to their diverse
applications in organic synthesis, coordination chemistry, as well as in the fields of drug …

Tubulin, an important clinical molecular target, has attracted high attention in drug design
development and cancer treatment. Tubulin inhibitors cause cell cycle arrest in the G 2/M …

A new series of styrylquinolines was designed and synthesized as anticancer agents and
tubulin polymerization inhibitors. The in vitro anticancer activity of the synthesized quinolines …

Natural compounds are rich in pharmacological properties that are a hot topic in
pharmaceutical research. The quinoline ring plays important roles in many biological …

Saccharomyces boulardii, a variety of S. cerevisiae, is used as a probiotic yeast in food and
drug industries. However, S. boulardii is an opportunistic pathogen, and the supernatant of …