The genetics of Kawasaki disease

Y Onouchi - International journal of rheumatic diseases, 2018 - Wiley Online Library
Kawasaki disease (KD) is a complex disorder which affects genetically susceptible infants
and children. Several susceptibility genes (eg, ITPKC, CASP 3, CD 40 and ORAI) and …

The etiologies of Kawasaki disease

JC Burns - The Journal of Clinical Investigation, 2024 - Am Soc Clin Investig
Kawasaki disease (KD) is a systemic vasculitis that affects young children and can result in
coronary artery aneurysms. The etiology is currently unknown, but new clues from the …

Biomarkers for Kawasaki disease: clinical utility and the challenges ahead

H Chaudhary, J Nameirakpam, R Kumrah… - Frontiers in …, 2019 - frontiersin.org
Kawasaki disease (KD) has replaced acute rheumatic fever as the most common cause of
acquired heart disease in children in the developed world and is increasingly being …

Coronary-artery aneurysm in tocilizumab-treated children with Kawasaki's disease

T Nozawa, T Imagawa, S Ito - New England Journal of Medicine, 2017 - Mass Medical Soc
Four patients with Kawasaki's disease resistant to IVIG treatment had a response to the anti–
interleukin-6 antibody tocilizumab, but coronary-artery aneurysms developed in two of the …

Delineating phenotypes of Kawasaki disease and SARS-CoV-2-related inflammatory multisystem syndrome: a French study and literature review

B Cherqaoui, I Koné-Paut, H Yager… - …, 2021 - academic.oup.com
Objective To better define the clinical distinctions between the new severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2)-related paediatric inflammatory multisystem …

Association of an IGHV3-66 gene variant with Kawasaki disease

TA Johnson, Y Mashimo, JY Wu, D Yoon… - Journal of human …, 2021 - nature.com
In a meta-analysis of three GWAS for susceptibility to Kawasaki disease (KD) conducted in
Japan, Korea, and Taiwan and follow-up studies with a total of 11,265 subjects (3428 cases …

Host/genetic factors associated with COVID-19 call for precision medicine

AR Thierry - Precision Clinical Medicine, 2020 - academic.oup.com
If the current rate of infection are to be better managed, and future waves of infection kept at
bay, it is absolutely necessary that the conditions and mechanisms of exposure to Severe …

Comparable bidirectional neutrophil immune dysregulation between Kawasaki disease and severe COVID-19

KD Chen, YH Huang, WS Wu, LS Chang… - Frontiers in …, 2022 - frontiersin.org
Kawasaki disease (KD), a multisystem inflammatory syndrome that occurs in children, and
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 or COVID-19) may share …

Kawasaki syndrome: role of superantigens revisited

DYM Leung, PM Schlievert - The FEBS Journal, 2021 - Wiley Online Library
Kawasaki syndrome (KS) is an acute vasculitis in children complicated by the development
of heart disease. Despite its description over 50 years ago, the etiology of coronary artery …

How to manage children if a second wave of COVID-19 occurs

S Esposito, S Zona, G Vergine, M Fantini… - … AND LUNG DISEASE, 2020 - air.unipr.it
Dear Editor, Many experts believe that those countries that presently have an acceptable
rate of COVID-19 transmission may experience a second wave of COVID-19 as we enter the …