Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells

JS Brody, A Spira, JS Berman… - US Patent App. 12 …, 2009 - Google Patents
0003 1. Field of the Invention 0004. The present invention is directed to methods for
diagnosing lung diseases from nasal epithelial cells using gene expression analysis. More …

Detection methods for disorders of the lung

J Brody, A Spira - US Patent App. 11/294,834, 2006 - Google Patents
The present invention is directed to prognostic and diagnos tic methods to assess lung
disease risk caused by airway pollutants by analyzing expression of one or more genes …

Diagnostic for lung disorders using class prediction

JS Brody, A Spira - US Patent App. 11/918,588, 2010 - Google Patents
The present invention provides methods for diagnosis and prognosis of lung cancer using
expression analysis of one or more groups of genes, and a combination of expression analy …

Multifactorial methods for detecting lung disorders

A Spira, ME Lenburg, JE Beane-Ebel… - US Patent App. 12 …, 2010 - Google Patents
The invention described herein relates to multifac torial methods for detecting, diagnosing or
aiding in the diag nosis of lung disorders or disease, eg, lung cancer. The methods of the …

Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions

JE Beane-Ebel, A Tassinari, A Spira… - US Patent …, 2021 - Google Patents
2005/0260586 A1 2005/0266409 A1 2006/0127928 Al 2006/0140960 A1 2006/0154278 Al
2006/0183144 Al 2006/0188909 A1 2006/0190192 A1 2006/0194216 A1 2007/0092891 Al …

Methods for evaluating COPD status

DH Whitney, J Luo - US Patent 10,526,655, 2020 - Google Patents
The invention in some aspects provides methods of deter mining the likelihood that a subject
has COPD based on the expression of informative-genes. In other aspects, the inven tion …

Isolation of nucleic acid from mouth epithelial cells

JS Brody, A Spira - US Patent App. 12/351,484, 2009 - Google Patents
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sat 200599 Sat 2008.63 sat 201923 at 208918s at 208919 is at 2024.81 at 204500s at …

Diagnostic for lung disorders using class prediction

JS Brody, A Spira, JE Beane-Ebel… - US Patent …, 2020 - Google Patents
The present invention provides methods for diagnosis and prognosis of lung cancer using
expression analysis of one or more groups of genes, and a combination of expression …

Methods of identifying individuals at increased risk of lung cancer

JS Brody, A Spira, A Gustafson, A Bild - US Patent 10,570,454, 2020 - Google Patents
The invention provides the identification of oncogenic pathways activated in cytologically
normal airway cells of individuals having or at risk of having lung disease, as well as specific …

Diagnostic for lung disorders using class prediction

JS Brody, A Spira, JE Beane-Ebel… - US Patent …, 2018 - Google Patents
The present invention provides methods for diagnosis and prognosis of lung cancer using
expression analysis of one or more groups of genes, and a combination of expression …