Video-based screening of pooled libraries is a powerful approach for directed evolution of
biosensors because it enables selection along multiple dimensions simultaneously from …

Objective. Various on-workstation neural-spike-based brain machine interface (BMI)
systems have reached the point of in-human trials, but on-node and on-implant BMI systems …

Neuronal firing rate is traditionally defined as the number of spikes per time window. The
concept is essential for the rate coding hypothesis, which is still the most commonly …

All-optical electrophysiology can be a powerful tool for studying neural dynamics in vivo, as
it offers the ability to image and perturb membrane voltage in multiple cells simultaneously …

Persistence reinforces continuous action, which benefits animals in many aspects. Diverse
external or internal signals may trigger animals to start a persistent movement. However, it is …

Cognitive and behavioral rigidity are observed in various psychiatric diseases, including in
autism spectrum disorder (ASD). However, the underlying mechanism remains to be …

Central to advancing our understanding of neural circuits is developing minimally invasive,
multi-modal interfaces capable of simultaneously recording and modulating neural activity …

To understand the information processing mechanism of the brain, it is important to decode
the bidirectional communication between the brain and organs. For this purpose …

The rate coding hypothesis is the oldest and still one of the most accepted hypotheses of
neural coding. Consequently, many approaches have been devised for the firing rate …

The functional interactions between the brain and heart through analysis of electrical activity
(EEG and ECG) provide effective bio-markers for cognition, emotions, and morbidity …