Mitochondrial Dysfunction in Metabolic Dysfunction Fatty Liver Disease (MAFLD)

Y Zhao, Y Zhou, D Wang, Z Huang, X Xiao… - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) has become an increasingly common disease in
Western countries and has become the major cause of liver cirrhosis or hepatocellular …

[HTML][HTML] Biological activities, Molecular mechanisms, and Clinical application of Naringin in Metabolic syndrome

J Chen, X Qin, M Chen, T Chen, Z Chen, B He - Pharmacological Research, 2024 - Elsevier
Metabolic syndrome has become major health problems in recent decades, and natural
compounds receive considerable attention in the management of metabolic syndrome …

Naringin from sweet orange peel improves testicular function in high fat diet-induced diabetic rats by modulating xanthine oxidase/uric acid signaling and maintaining …

KB Okesina, AF Odetayo, WJ Adeyemi… - Laboratory Animal …, 2024 - Springer
Background Type 2 diabetes mellitus (T2DM) is a metabolic disorder affecting many organs,
including the testis. Naringin from orange peel extract (OPE) is a flavanone with fertility …

The NRF-2/HO-1 signaling pathway: a promising therapeutic target for metabolic dysfunction-associated steatotic liver disease

N Li, L Hao, S Li, J Deng, F Yu, J Zhang… - Journal of …, 2024 - Taylor & Francis
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a progressive liver
disorder with a rising prevalence. It begins with lipid accumulation in hepatocytes and …

Regulatory mechanism and therapeutic potentials of naringin against inflammatory disorders

Y Peng, R Qu, S Xu, H Bi, D Guo - Heliyon, 2024 - cell.com
Naringin is a natural flavonoid with therapeutic properties found in citrus fruits and an active
natural product from herbal plants. Naringin has become a focus of attention in recent years …

Examining the Pathogenesis of MAFLD and the Medicinal Properties of Natural Products from a Metabolic Perspective

Y Fu, Z Wang, H Qin - Metabolites, 2024 - mdpi.com
Metabolic-associated fatty liver disease (MAFLD), characterized primarily by hepatic
steatosis, has become the most prevalent liver disease worldwide, affecting approximately …

Plant-Derived Nrf2 Activators to Enhance Liver Antioxidative and Regenerative Potentials

TX Tee, LT Kee, TT Chai, HC Yam, HM Reza… - Revista Brasileira de …, 2024 - Springer
Excessive reactive oxygen species are harmful to human health due to the spontaneous
oxidation of intracellular biomolecules such as deoxyribonucleic acid and proteins. To …

Effects of Full-Spectrum Cannabis Oil with a Cannabidiol: Tetrahydrocannabinol 2: 1 Ratio on the Mechanisms Involved in Hepatic Steatosis and Oxidative Stress in …

V Degrave, MB Vega Joubert, P Ingaramo… - Medical Cannabis and …, 2023 - karger.com
Introduction: This study aimed to analyze the effects of cannabis oil (cannabidiol:
tetrahydrocannabinol [CBD: THC], 2: 1 ratio) on the mechanisms involved in hepatic …

血红素氧合酶1 调节铁死亡在非酒精性脂肪性肝病中的研究进展

曹佳岑, 张宏坤, 赵文, 南月敏, 李冬冬 - 中国全科医学, 2024 - chinagp.net
铁死亡是一种新型的细胞程序性死亡方式, 在非酒精性脂肪性肝病(NAFLD)
进展中发挥重要作用. 研究表明, 作为一种诱导型氧化酶, 血红素氧合酶1 (HO-1) …

Active-phase Plasma Alkaline Phosphatase Isozyme Activity Is a Sensitive Biomarker for Excessive Fructose Intake

Y Suzuki, D Yokoyama, C Matsuura, K Kondo… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Excessive fructose intake reportedly leads to the development of
nonalcoholic fatty liver disease (NAFLD). In our previous study, we reported that plasma …