[HTML][HTML] Emerging trends and innovations in the treatment and diagnosis of atherosclerosis and cardiovascular disease: a comprehensive review towards healthier …

I Alradwan, N Al Fayez, MN Alomary, AA Alshehri… - Pharmaceutics, 2024 - mdpi.com
Cardiovascular diseases (CVDs) are classed as diseases of aging, which are associated
with an increased prevalence of atherosclerotic lesion formation caused by such diseases …

Applications and research advances in the delivery of CRISPR/Cas9 systems for the treatment of inherited diseases

X Lu, M Zhang, G Li, S Zhang, J Zhang, X Fu… - International journal of …, 2023 - mdpi.com
The rapid advancements in gene therapy have opened up new possibilities for treating
genetic disorders, including Duchenne muscular dystrophy, thalassemia, cystic fibrosis …

mRNA therapies: Pioneering a new era in rare genetic disease treatment

G Shen, J Liu, H Yang, N Xie, Y Yang - Journal of Controlled Release, 2024 - Elsevier
Rare genetic diseases, often referred to as orphan diseases due to their low prevalence and
limited treatment options, have long posed significant challenges to our medical system. In …

Established and Emerging Nucleic Acid Therapies for Familial Hypercholesterolemia

TR Damase, R Sukhovershin, B Godin, K Nasir… - Circulation, 2024 - ahajournals.org
Familial hypercholesterolemia (FH) is a genetic disease that leads to elevated low-density
lipoprotein cholesterol levels and risk of coronary heart disease. Current therapeutic options …