[HTML][HTML] Maternal immunological adaptation during normal pregnancy

B Abu-Raya, C Michalski, M Sadarangani… - Frontiers in …, 2020 - frontiersin.org
The risk and severity of specific infections are increased during pregnancy due to a
combination of physiological and immunological changes. Characterizing the maternal …

[HTML][HTML] T helper (Th) cell profiles in pregnancy and recurrent pregnancy losses: Th1/Th2/Th9/Th17/Th22/Tfh cells

W Wang, N Sung, A Gilman-Sachs… - Frontiers in …, 2020 - frontiersin.org
During pregnancy, various immune effectors and molecules participating in the immune-
microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus …

[HTML][HTML] Sex differences in immunity to viral infections

H Jacobsen, SL Klein - Frontiers in immunology, 2021 - frontiersin.org
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences
in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias …

Estradiol, progesterone, immunomodulation, and COVID-19 outcomes

F Mauvais-Jarvis, SL Klein, ER Levin - Endocrinology, 2020 - academic.oup.com
Severe outcomes and death from the novel coronavirus disease 2019 (COVID-19) appear to
be characterized by an exaggerated immune response with hypercytokinemia leading to …

[HTML][HTML] Sex differences in immune responses

SL Klein, KL Flanagan - Nature Reviews Immunology, 2016 - nature.com
Males and females differ in their immunological responses to foreign and self-antigens and
show distinctions in innate and adaptive immune responses. Certain immunological sex …

[HTML][HTML] Cytokines, hormones and cellular regulatory mechanisms favoring successful reproduction

MP Piccinni, R Raghupathy, S Saito… - Frontiers in …, 2021 - frontiersin.org
Its semi-allogeneic nature renders the conceptus vulnerable to attack by the maternal
immune system. Several protective mechanisms operate during gestation to correct the …

Sex and gender differences in bacterial infections

SP Dias, MC Brouwer, D van de Beek - Infection and Immunity, 2022 - Am Soc Microbiol
There is a growing awareness of the importance of sex and gender in medicine and
research. Women typically have stronger immune responses to self and foreign antigens …

[HTML][HTML] Gender differences in autoimmune disease

ST Ngo, FJ Steyn, PA McCombe - Frontiers in neuroendocrinology, 2014 - Elsevier
Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …

The endocrine function of human placenta: an overview

MA Costa - Reproductive biomedicine online, 2016 - Elsevier
During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …

Sex differences in immune responses: Hormonal effects, antagonistic selection, and evolutionary consequences

J Roved, H Westerdahl, D Hasselquist - Hormones and behavior, 2017 - Elsevier
Males and females differ in both parasite load and the strength of immune responses and
these effects have been verified in humans and other vertebrates. Sex hormones act as …