The onset of heart failure is typically preceded by cardiac hypertrophy, a response of the
heart to increased workload, a cardiac insult such as a heart attack or genetic mutation …

Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Protein kinase C (PKC) has been a tantalizing target for drug discovery ever since it was first
identified as the receptor for the tumour promoter phorbol ester in 1982. Although initial …

Cardiovascular disease is the number one cause of mortality in the Western world. The heart
responds to many cardiopathological conditions with hypertrophic growth by enlarging …

Cardiovascular disease is the most common cause of death among diabetic patients
worldwide. Hence, cardiovascular wellbeing in diabetic patients requires utmost importance …

IRS proteins are cellular adaptor molecules that mediate many of the key metabolic actions
of insulin. When tyrosine is phosphorylated by the activated insulin receptor, IRS proteins …

In recent years, interest in non-coding RNAs as important physiological regulators has
grown significantly. Their participation in the pathophysiology of cardiovascular diseases is …

The protein kinase C (PKC) and closely related protein kinase N (PKN) families of
serine/threonine protein kinases play crucial cellular roles. Both kinases belong to the AGC …

Ischemic stroke and Alzheimer's disease (AD), despite being distinct disease entities, share
numerous pathophysiological mechanisms such as those mediated by inflammation …

Background/Aims: Myocardial infarction (MI) is a serious complication of atherosclerosis
associated with increasing mortality attributable to heart failure. This study is aimed to …