Functional connectivity in multiple sclerosis: recent findings and future directions

M Tahedl, SM Levine, MW Greenlee, R Weissert… - Frontiers in …, 2018 - frontiersin.org
Multiple sclerosis is a debilitating disorder resulting from scattered lesions in the central
nervous system. Because of the high variability of the lesion patterns between patients, it is …

The role of the cerebellum in multiple sclerosis—150 years after Charcot

K Parmar, C Stadelmann, MA Rocca, D Langdon… - Neuroscience & …, 2018 - Elsevier
Despite its functional importance and well known clinical impact in Multiple Sclerosis (MS),
the cerebellum has only received significant attention over the past few years. It is now …

Brain dysconnectivity relates to disability and cognitive impairment in multiple sclerosis

M Sjøgård, V Wens, J Van Schependom… - Human brain …, 2021 - Wiley Online Library
The pathophysiology of cognitive dysfunction in multiple sclerosis (MS) is still unclear. This
magnetoencephalography (MEG) study investigates the impact of MS on brain resting‐state …

Structural brain network characteristics can differentiate CIS from early RRMS

M Muthuraman, V Fleischer, P Kolber… - Frontiers in …, 2016 - frontiersin.org
Focal demyelinated lesions, diffuse white matter (WM) damage, and gray matter (GM)
atrophy influence directly the disease progression in patients with multiple sclerosis. The …

The role of the cerebellum in multiple sclerosis

K Weier, B Banwell, A Cerasa, DL Collins… - The Cerebellum, 2015 - Springer
In multiple sclerosis (MS), cerebellar signs and symptoms as well as cognitive dysfunction
are frequent and contribute to clinical disability with only poor response to symptomatic …

[HTML][HTML] The role of the cerebellum in multiple sclerosis: structural damage and disconnecting networks

EJP Brouwer, M Strik, MM Schoonheim - Current Opinion in Behavioral …, 2024 - Elsevier
Highlights•Multiple sclerosis commonly features cerebellar pathology, which remains
understudied•Cerebellar lesions and neurodegeneration impact both motor and cognitive …

Synaptic pathology in the cerebellar dentate nucleus in chronic multiple sclerosis

M Albert, A Barrantes‐Freer, M Lohrberg… - Brain …, 2017 - Wiley Online Library
In multiple sclerosis, cerebellar symptoms are associated with clinical impairment and an
increased likelihood of progressive course. Cortical atrophy and synaptic dysfunction play a …

Axonal loss in major sensorimotor tracts is associated with impaired motor performance in minimally disabled multiple sclerosis patients

M Strik, LE Cofré Lizama, CJ Shanahan… - Brain …, 2021 - academic.oup.com
Multiple sclerosis is a neuroinflammatory disease of the CNS that is associated with
significant irreversible neuro-axonal loss, leading to permanent disability. There is thus an …

Functionally relevant white matter degradation in multiple sclerosis: a tract-based spatial meta-analysis

T Welton, D Kent, CS Constantinescu, DP Auer… - Radiology, 2015 - pubs.rsna.org
Purpose To identify statistical consensus between published studies for distribution and
functional relevance of tract white matter (WM) degradation in multiple sclerosis (MS) …

Evidence for early, non-lesional cerebellar damage in patients with multiple sclerosis: DTI measures correlate with disability, atrophy, and disease duration

M Deppe, K Tabelow, J Krämer… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Common symptoms of multiple sclerosis (MS) such as gait ataxia, poor
coordination of the hands, and intention tremor are usually the result of dysfunctionality in …