Our understanding of human disorders that affect higher cognitive functions has greatly
advanced in recent decades, and over 20 genes associated with non-syndromic mental …

For immobile plants, the main means of protection against adverse environmental factors is
the biosynthesis of various secondary (specialized) metabolites. The extreme diversity and …

Background Pharmacogenetic determinants of the response of patients to clopidogrel
contribute to variability in the biologic antiplatelet activity of the drug. The effect of these …

Autistic-spectrum conditions and psychotic-spectrum conditions (mainly schizophrenia,
bipolar disorder, and major depression) represent two major suites of disorders of human …

Autism is a heterogeneous condition that is likely to result from the combined effects of
multiple genetic factors interacting with environmental factors. Given its complexity, the study …

Emerging evidence associates dysfunction in the dopamine (DA) transporter (DAT) with the
pathophysiology of autism spectrum disorder (ASD). The human DAT (hDAT; SLC6A3) rare …

Autism spectrum disorders is a heterogenous group of neurodevelopmental disorders, the
etiology or etiologies of which remain unknown. Increasing evidence of autoimmune …

Autism and autism-spectrum disorders exhibit high heritability, although specific
susceptibility genes still remain largely elusive. We performed a heterogeneity-based …

Schizophrenia (SZ) and autism spectrum disorders (ASD) are characterised by marked
language deficits, but it is not clear how these arise from gene mutations associated with the …

Autism is a neurodevelopmental disorder with high heritability and a likely complex genetic
architecture. Much genetic evidence has accumulated in the last 20 years but no gene has …