Can insects feel pain? A review of the neural and behavioural evidence

M Gibbons, A Crump, M Barrett, S Sarlak, J Birch… - Advances in Insect …, 2022 - Elsevier
The entomology literature has historically suggested insects cannot feel pain, leading to
their exclusion from ethical debates and animal welfare legislation. However, there may be …

Eukaryotic mechanosensitive channels

J Árnadóttir, M Chalfie - Annual review of biophysics, 2010 - annualreviews.org
Mechanosensitive ion channels are gated directly by physical stimuli and transduce these
stimuli into electrical signals. Several criteria must apply for a channel to be considered …

A multilevel multimodal circuit enhances action selection in Drosophila

T Ohyama, CM Schneider-Mizell, RD Fetter, JV Aleman… - Nature, 2015 - nature.com
Natural events present multiple types of sensory cues, each detected by a specialized
sensory modality. Combining information from several modalities is essential for the …

The role of Drosophila Piezo in mechanical nociception

SE Kim, B Coste, A Chadha, B Cook, A Patapoutian - Nature, 2012 - nature.com
Transduction of mechanical stimuli by receptor cells is essential for senses such as hearing,
touch and pain,,,. Ion channels have a role in neuronal mechanotransduction in …

Light-avoidance-mediating photoreceptors tile the Drosophila larval body wall

Y Xiang, Q Yuan, N Vogt, LL Looger, LY Jan, YN Jan - Nature, 2010 - nature.com
Photoreceptors for visual perception, phototaxis or light avoidance are typically clustered in
eyes or related structures such as the Bolwig organ of Drosophila larvae. Unexpectedly, we …

Nociceptive neurons protect Drosophila larvae from parasitoid wasps

RY Hwang, L Zhong, Y Xu, T Johnson, F Zhang… - Current biology, 2007 - cell.com
Background Natural selection has resulted in a complex and fascinating repertoire of innate
behaviors that are produced by insects. One puzzling example occurs in fruit fly larvae that …

The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals

R O'Hagan, M Chalfie, MB Goodman - Nature neuroscience, 2005 - nature.com
Transformation of mechanical energy into ionic currents is essential for touch, hearing and
nociception. Although DEG/ENaC proteins are believed to form sensory …

Nociceptors: a phylogenetic view

ESJ Smith, GR Lewin - Journal of Comparative Physiology A, 2009 - Springer
The ability to react to environmental change is crucial for the survival of an organism and an
essential prerequisite is the capacity to detect and respond to aversive stimuli. The …

Neurosensory mechanotransduction

M Chalfie - Nature reviews Molecular cell biology, 2009 - nature.com
Neurons that sense touch, sound and acceleration respond rapidly to specific mechanical
signals. The proteins that transduce these signals and underlie these senses, however, are …

Discovery of brainwide neural-behavioral maps via multiscale unsupervised structure learning

JT Vogelstein, Y Park, T Ohyama, RA Kerr, JW Truman… - Science, 2014 - science.org
A single nervous system can generate many distinct motor patterns. Identifying which
neurons and circuits control which behaviors has been a laborious piecemeal process …