WNT signaling in melanoma
A Gajos-Michniewicz, M Czyz - International journal of molecular sciences, 2020 - mdpi.com
WNT-signaling controls important cellular processes throughout embryonic development
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …
and adult life, so any deregulation of this signaling can result in a wide range of pathologies …
Dermatophyte resistance to antifungal drugs: mechanisms and prospectus
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …
structures present in nails, skin, and hair, causing superficial infections known as …
Fungal cell membrane—promising drug target for antifungal therapy
Increase in invasive fungal infections over the past few years especially in
immunocompromised patients prompted the search for new antifungal agents with improved …
immunocompromised patients prompted the search for new antifungal agents with improved …
New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
The role of eukaryotic and prokaryotic ABC transporter family in failure of chemotherapy
R El-Awady, E Saleh, A Hashim, N Soliman… - Frontiers in …, 2017 - frontiersin.org
Over the years chemotherapy failure has been a vital research topic as researchers have
been striving to discover reasons behind it. The extensive studies carried out on …
been striving to discover reasons behind it. The extensive studies carried out on …
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design
The cytochrome P450 enzyme lanosterol 14α-demethylase (LDM) is the target of the azole
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
[HTML][HTML] Suppl 1: microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation
Conventional antimicrobials are increasingly ineffective due to the emergence of multidrug-
resistance among pathogenic microorganisms. The need to overcome these deficiencies …
resistance among pathogenic microorganisms. The need to overcome these deficiencies …
Targeting efflux pumps to overcome antifungal drug resistance
AR Holmes, TS Cardno, JJ Strouse… - Future Medicinal …, 2016 - Taylor & Francis
Resistance to antifungal drugs is an increasingly significant clinical problem. The most
common antifungal resistance encountered is efflux pump-mediated resistance of Candida …
common antifungal resistance encountered is efflux pump-mediated resistance of Candida …
Antimicrobial properties of antidepressants and antipsychotics—possibilities and implications
M Caldara, N Marmiroli - Pharmaceuticals, 2021 - mdpi.com
The spreading of antibiotic resistance is responsible annually for over 700,000 deaths
worldwide, and the prevision is that this number will increase exponentially. The …
worldwide, and the prevision is that this number will increase exponentially. The …
Potent synergistic interactions between lopinavir and azole antifungal drugs against emerging multidrug-resistant Candida auris
The limited therapeutic options and the recent emergence of multidrug-resistant Candida
species present a significant challenge to human medicine and underscore the need for …
species present a significant challenge to human medicine and underscore the need for …