[HTML][HTML] Paracrine mechanisms of endothelial progenitor cells in vascular repair

F Yan, X Liu, H Ding, W Zhang - Acta Histochemica, 2022 - Elsevier
Endothelial progenitor cells (EPCs) play an important role in repairing damaged blood
vessels and promoting neovascularization. However, the specific mechanism of EPCs …

Tissue regeneration using endothelial colony-forming cells: promising cells for vascular repair

K Banno, MC Yoder - Pediatric research, 2018 - nature.com
Repairing and rebuilding damaged tissue in diseased human subjects remains a daunting
challenge for clinical medicine. Proper vascular formation that serves to deliver blood-borne …

Recent advances in endothelial colony forming cells toward their use in clinical translation

KE Paschalaki, AM Randi - Frontiers in medicine, 2018 - frontiersin.org
The term “Endothelial progenitor cell”(EPC) has been used to describe multiple cell
populations that express endothelial surface makers and promote vascularisation. However …

Receptor-ligand interaction mediates targeting of endothelial colony forming cell-derived exosomes to the kidney after ischemic injury

JL Viñas, M Spence, A Gutsol, W Knoll, D Burger… - Scientific reports, 2018 - nature.com
Endothelial colony forming cell (ECFC)-derived exosomes protect mice against ischemic
kidney injury, via transfer of microRNA-(miR)-486-5p. Mechanisms mediating exosome …

Endothelial progenitor cells dysfunctions and cardiometabolic disorders: from mechanisms to therapeutic approaches

AC Peyter, JB Armengaud, E Guillot… - International Journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) is a cluster of several disorders, such as hypertension, central
obesity, dyslipidemia, hyperglycemia, insulin resistance and non-alcoholic fatty liver …

Advances in cell therapies using stem cells/progenitors as a novel approach for neurovascular repair of the diabetic retina

J Lechner, RJ Medina, N Lois, AW Stitt - Stem Cell Research & Therapy, 2022 - Springer
Background Diabetic retinopathy, a major complication of diabetes mellitus, is a leading
cause of sigh-loss in working age adults. Progressive loss of integrity of the retinal …

Activation of angiopoietin-tie2 signaling protects the kidney from ischemic injury by modulation of endothelial-specific pathways

Y Li, P Liu, Y Zhou, H Maekawa, JB Silva… - Journal of the …, 2023 - journals.lww.com
Background Ischemia-reperfusion AKI (IR-AKI) is estimated to affect 2%–7% of all
hospitalized patients. The significant morbidity and mortality associated with AKI indicates …

Cyclosporine A and tacrolimus induce functional impairment and inflammatory reactions in endothelial progenitor cells

N Meyer, L Brodowski, C von Kaisenberg… - International Journal of …, 2021 - mdpi.com
Immunosuppressants are a mandatory therapy for transplant patients to avoid rejection of
the transplanted organ by the immune system. However, there are several known side …

Nephroprotective Effects of Cardamonin on Renal Ischemia Reperfusion Injury/UUO-Induced Renal Fibrosis

B Zhang, ZY Chen, Z Jiang, S Huang… - Journal of Agricultural …, 2023 - ACS Publications
Acute kidney injury and chronic renal fibrosis are intractable pathological processes to
resolve, yet limited strategies are able to effectively address them. Cardamonin (CAD) is a …

Time-and gender-dependent alterations in mice during the aging process

J Jin, X Yang, H Gong, X Li - International Journal of Molecular Sciences, 2023 - mdpi.com
Compared to young people and adults, there are differences in the ability of elderly people
to resist diseases or injuries, with some noticeable features being gender-dependent …