Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

Arrhythmogenic right ventricular cardiomyopathy is a rare inherited heart-muscle disease
that is a cause of sudden death in young people and athletes. Causative mutations in genes …

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVC) is a genetic disease
caused by mutations in desmosomal proteins. The phenotypic hallmark of ARVC is …

Cardiovascular diseases represent a major cause of morbidity and mortality, necessitating
research to improve diagnostics, and to discover and test novel preventive and curative …

Intercellular communication is essential for proper cardiac function. Mechanical and
electrical activity need to be synchronized so that the work of individual myocytes transforms …

Aims Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by right
ventricular myocardial replacement and life-threatening ventricular arrhythmias …

Mitral valve competence requires complex interplay between structures that comprise the
mitral apparatus–the mitral annulus, mitral valve leaflets, chordae tendineae, papillary …

Aims Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary heart muscle
disorder associated with sudden cardiac death. Its pathophysiology is still poorly …

Arrhythmogenic right ventricular cardiomyopathy (ARVC) has a prevalence of at least 1 in
1000, is a leading cause of sudden cardiac death in people aged≤ 35 years, and accounts …

Due to the biological complexity of the cardiovascular system, the animal model is an urgent
pre-clinical need to advance our knowledge of cardiovascular disease and to explore new …