Immune cell phenotype and function in sepsis

T Rimmelé, D Payen, V Cantaluppi, J Marshall… - Shock, 2016 - journals.lww.com
Cells of the innate and adaptive immune systems play a critical role in the host response to
sepsis. Moreover, their accessibility for sampling and their capacity to respond dynamically …

Viral endothelial dysfunction: A unifying mechanism for COVID-19

M Prasad, M Leon, LO Lerman, A Lerman - Mayo Clinic Proceedings, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
transmissible virus with significant global impact, morbidity, and mortality. The SARS-CoV-2 …

Renoprotective approaches and strategies in acute kidney injury

Y Yang, M Song, Y Liu, H Liu, L Sun, Y Peng… - Pharmacology & …, 2016 - Elsevier
Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and
increasing prevalence. Decades of research have suggested numerous chemical and …

Endothelial progenitor cells in the host defense response

X Shi, KA Seidle, KJ Simms, F Dong, WM Chilian… - Pharmacology & …, 2023 - Elsevier
Extensive injury of endothelial cells in blood vasculature, especially in the microcirculatory
system, frequently occurs in hosts suffering from sepsis and the accompanied systemic …

[HTML][HTML] Microparticles: markers and mediators of sepsis-induced microvascular dysfunction, immunosuppression, and AKI

ACP Souza, PST Yuen, RA Star - Kidney international, 2015 - Elsevier
Sepsis is a severe and complex syndrome that lacks effective prevention or therapeutics.
The effects of sepsis on the microvasculature have become an attractive area for possible …

Blood vessels and peripheral nerves as key players in cancer progression and therapy resistance

N Roda, G Blandano, PG Pelicci - Cancers, 2021 - mdpi.com
Simple Summary The interactions between cancer cells and the surrounding blood vessels
and peripheral nerves are critical in all the phases of tumor development. Accordingly …

In acute kidney injury, indoxyl sulfate impairs human endothelial progenitor cells: modulation by statin

VC Wu, GH Young, PH Huang, SC Lo, KC Wang… - Angiogenesis, 2013 - Springer
Renal ischemia rapidly mobilizes endothelial progenitor cells (EPCs), which provides
renoprotection in acute kidney injury (AKI). Indoxyl sulfate (IS) is a protein-binding uremic …

Endothelial progenitor cells and a stromal cell–derived factor-1α analogue synergistically improve survival in sepsis

H Fan, AJ Goodwin, E Chang, B Zingarelli… - American journal of …, 2014 - atsjournals.org
Rationale: Endothelial progenitor cells (EPCs) have been associated with human sepsis but
their role is incompletely understood. Stromal cell–derived factor (SDF)-1α facilitates EPC …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

Cellular immuno-profile in septic human host: a scoping review

C Zanza, G Caputo, G Tornatore, T Romenskaya… - Biology, 2022 - mdpi.com
Simple Summary Septic shock is a life-threatening disease caused by a dysregulated host
response to infection, affecting millions of people every year and killing more than 25 …